The effect of contact angles and capillary dimensions on the burst frequency of super hydrophilic and hydrophilic centrifugal microfluidic platforms, a CFD study

Kazemzadeh, A. and Ganesan, P. and Ibrahim, Fatimah and He, S. and Madou, M.J. (2013) The effect of contact angles and capillary dimensions on the burst frequency of super hydrophilic and hydrophilic centrifugal microfluidic platforms, a CFD study. PLoS ONE, 8 (9). pp. 1-12. ISSN 1932-6203, DOI

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This paper employs the volume of fluid (VOF) method to numerically investigate the effect of the width, height, and contact angles on burst frequencies of super hydrophilic and hydrophilic capillary valves in centrifugal microfluidic systems. Existing experimental results in the literature have been used to validate the implementation of the numerical method. The performance of capillary valves in the rectangular and the circular microfluidic structures on super hydrophilic centrifugal microfluidic platforms is studied. The numerical results are also compared with the existing theoretical models and the differences are discussed. Our experimental and computed results show a minimum burst frequency occurring at square capillaries and this result is useful for designing and developing more sophisticated networks of capillary valves. It also predicts that in super hydrophilic microfluidics, the fluid leaks consistently from the capillary valve at low pressures which can disrupt the biomedical procedures in centrifugal microfluidic platforms. © 2013 Kazemzadeh et al.

Item Type: Article
Additional Information: Export Date: 29 January 2014 Source: Scopus Art. 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Uncontrolled Keywords: capillary density; capillary pressure; centrifugal microfluidic platform; computational fluid dynamics; computer simulation; contact angle; hydrophilicity; hydrophobicity; mathematical computing; microfluidic analysis; theoretical model; validation process
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 12 Feb 2014 01:22
Last Modified: 06 Feb 2020 04:01

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