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Lim, Andy Shing Seng and Tan, Kae Yi and Tan, Choo Hock (2024) Immunoreactivity and neutralization efficacy of Pakistani Viper Antivenom (PVAV) against venoms of Saw-scaled Vipers (Echis carinatus subspp.) and Western Russell's Vipers (Daboia russelii) from the Indian subcontinent. Acta Tropica, 250. p. 107099. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2023.107099.
Lee, Louisa Pernee and Tan, Choo Hock and Khomvilai, Sumana and Sitprija, Visith and Chaiyabutr, Narongsak and Tan, Kae Yi (2023) Characterizing and applying immunoglobulins in snakebite diagnostics: A simple and rapid venom detection assay for four medically important snake species in Southeast Asia. International Journal of Biological Macromolecules, 236. ISSN 0141-8130, DOI https://doi.org/10.1016/j.ijbiomac.2023.123727.
Lim, Andy Shing Seng and Tan, Kae Yi and Quraishi, Naeem H. and Farooque, Saud and Khoso, Zahoor Ahmed and Ratanabanangkoon, Kavi and Tan, Choo Hock (2023) Proteomic analysis, immuno-specificity and neutralization efficacy of Pakistani viper antivenom (pvav), a bivalent anti-viperid antivenom produced in Pakistan. Toxins, 15 (4). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins15040265.
Chan, Yi Wei and Tan, Choo Hock and Heh, Choon Han and Tan, Kae Yi (2023) An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms. Frontiers in Pharmacology, 14. ISSN 1663-9812, DOI https://doi.org/10.3389/fphar.2023.1143437.
Blessmann, Joerg and Hanlodsomphou, Soulaphab and Santisouk, Bounlom and Krumkamp, Ralf and Kreuels, Benno and Ismail, Ahmad Khaldun and Yong, Mun Yee and Tan, Kae Yi and Tan, Choo Hock (2023) Experience of using expired lyophilized snake antivenom during a medical emergency situation in Lao People's Democratic Republic: A possible untapped resource to tackle antivenom shortage in Southeast Asia. Tropical Medicine and International Health, 28 (1). pp. 64-70. ISSN 1360-2276, DOI https://doi.org/10.1111/tmi.13833.
Tan, Choo Hock and Wong, Kin Ying and Huang, Li-Kun and Tan, Kae Yi and Tan, Nget Hong and Wu, Wen-Guey (2022) Snake venomics and antivenomics of cape cobra (Naja nivea) from South Africa: Insights into venom toxicity and cross-neutralization activity. Toxins, 14 (12). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins14120860.
Ong, Hui LinG and Tan, Choo Hock and Lee, Louisa Pernee and Khor, Sook Mei and Tan, Kae Yi (2022) An immunodetection assay developed using cobra cytotoxin-specific antibodies: Potential diagnostics for cobra envenoming. TOXICON, 216. pp. 157-168. ISSN 1879-3150, DOI https://doi.org/10.1016/j.toxicon.2022.07.010.
Tan, Choo Hock and Tan, Kae Yi and Wong, Kin Ying and Tan, Nget Hong and Chong, Ho Phin (2022) Equatorial spitting cobra (naja sumatrana) from Malaysia (Negeri Sembilan and Penang), Southern Thailand, and Sumatra: Comparative venom proteomics, immunoreactivity and cross-neutralization by antivenom. Toxins, 14 (8). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins14080522.
Tan, Kae Yi and Shamsuddin, Nor Naimah and Tan, Choo Hock (2022) Sharp-nosed Pit Viper (Deinagkistrodon acutus) from Taiwan and China: A comparative study on venom toxicity and neutralization by two specific antivenoms across the Strait. Acta Tropica, 232. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2022.106495.
Chong, Ho Phin and Tan, Kae Yi and Liu, Bing-Sin and Sung, Wang-Chou and Tan, Choo Hock (2022) Cytotoxicity of Venoms and Cytotoxins from Asiatic Cobras (Naja kaouthia, Naja sumatrana, Naja atra) and Neutralization by Antivenoms from Thailand, Vietnam, and Taiwan. Toxins, 14 (5). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins14050334.
Tan, Choo Hock (2022) Snake venomics: Fundamentals, recent updates, and a look to the next decade. Toxins, 14 (4). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins14040247.
Tan, Choo Hock and Lingam, Thava Malar Changra and Tan, Kae Yi (2022) Varespladib (LY315920) rescued mice from fatal neurotoxicity caused by venoms of five major Asiatic kraits (Bungarus spp.) in an experimental envenoming and rescue model. Acta Tropica, 227. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2021.106289.
Dashevsky, Daniel and Deuis, Jennifer R. and Vetter, Irina and Huynh, Tam and Hodgson, Wayne C. and Tan, Choo Hock and Nouwens, Amanda and Fry, Bryan G. (2022) Novel neurotoxic activity in calliophis intestinalis venom. Neurotoxicity Research, 40 (1). pp. 173-178. ISSN 1029-8428, DOI https://doi.org/10.1007/s12640-021-00413-2.
Tan, Choo Hock and Bourges, Aymeric and Tan, Kae Yi (2022) King Cobra and snakebite envenomation: On the natural history, human-snake relationship and medical importance of Ophiophagus hannah. Journal of Venomous Animals and Toxins including Tropical Diseases, 27. ISSN 1678-9199, DOI https://doi.org/10.1590/1678-9199-JVATITD-2021-0051.
Stazi, Marco and Fabris, Federico and Tan, Kae Yi and Megighian, Aram and Rubini, Alessandro and Mattarei, Andrea and Negro, Samuele and D'Este, Giorgia and Lista, Florigio and Rossetto, Ornella and Tan, Choo Hock and Montecucco, Cesare (2022) An agonist of the CXCR4 receptor is therapeutic for the neuroparalysis induced by Bungarus snakes envenoming. Clinical and Translational Medicine, 12 (1). ISSN 2001-1326, DOI https://doi.org/10.1002/ctm2.651.
Palasuberniam, Praneetha and Chan, Yi Wei and Tan, Kae Yi and Tan, Choo Hock (2021) Snake venom proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short alpha-neurotoxins as the dominant lethal component weakly cross-neutralized by the Philippine cobra antivenom. Frontiers in Pharmacology, 12. ISSN 1663-9812, DOI https://doi.org/10.3389/fphar.2021.727756.
Lingam, Thava Malar Changra and Tan, Kae Yi and Tan, Choo Hock (2021) Capillary leak syndrome induced by the venoms of Russell's Vipers (Daboia russelii and Daboia siamensis) from eight locales and neutralization of the differential toxicity by three snake antivenoms. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology, 250. ISSN 1532-0456, DOI https://doi.org/10.1016/j.cbpc.2021.109186.
Lee, Louisa Pernee and Tan, Kae Yi and Tan, Choo Hock (2021) Snake venom proteomics and antivenomics of two Sundaic lance-headed pit vipers: Trimeresurus wiroti (Malaysia) and Trimeresurus puniceus (Indonesia). Comparative Biochemistry and Physiology D-Genomics & Proteomics, 40. ISSN 1744-117X, DOI https://doi.org/10.1016/j.cbd.2021.100875.
Yong, Mun Yee and Tan, Kae Yi and Tan, Choo Hock (2021) Potential para-specific and geographical utility of Thai Green Pit Viper (Trimeresurus albolabris) Monovalent Antivenom: Neutralization of procoagulant and hemorrhagic activities of diverse Trimeresurus pit viper venoms. Toxicon, 203. pp. 85-92. ISSN 0041-0101, DOI https://doi.org/10.1016/j.toxicon.2021.09.021.
Palasuberniam, Praneetha and Tan, Kae Yi and Tan, Choo Hock (2021) De novo venom gland transcriptomics of Calliophis bivirgata flaviceps: Uncovering the complexity of toxins from the Malayan blue coral snake. Journal of Venomous Animals and Toxins including Tropical Diseases, 27. ISSN 1678-9199, DOI https://doi.org/10.1590/1678-9199-JVATITD-2021-0024.
Oh, Angeline Mei Feng and Tan, Kae Yi and Tan, Nget Hong and Tan, Choo Hock (2021) Proteomics and neutralization of Bungarus multicinctus (Many-banded Krait) venom: Intra-specific comparisons between specimens from China and Taiwan. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 247. ISSN 1532-0456, DOI https://doi.org/10.1016/j.cbpc.2021.109063.
Wong, Kin Ying and Tan, Kae Yi and Tan, Nget Hong and Gnanathasan, Christeine Ariaranee and Tan, Choo Hock (2021) Elucidating the venom diversity in Sri Lankan spectacled cobra (Naja naja) through de novo venom gland transcriptomics, venom proteomics and toxicity neutralization. Toxins, 13 (8). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins13080558.
Tan, Choo Hock and Palasuberniam, Praneetha and Tan, Kae Yi (2021) Snake venom proteomics, immunoreactivity and toxicity neutralization studies for the Asiatic Mountain Pit Vipers, Ovophis convictus, Ovophis tonkinensis, and Hime Habu, Ovophis okinavensis. Toxins, 13 (8). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins13080514.
Faisal, Tasnim and Tan, Kae Yi and Tan, Nget Hong and Sim, Si Mui and Gnanathasan, Christeine Ariaranee and Tan, Choo Hock (2021) Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms. Journal of Venomous Animals and Toxins including Tropical Diseases, 27. ISSN 1678-9199, DOI https://doi.org/10.1590/1678-9199-JVATITD-2020-0177.
Tan, Choo Hock and Bourges, Aymeric and Tan, Kae Yi (2021) King Cobra and snakebite envenomation: On the natural history, human-snake relationship and medical importance of Ophiophagus hannah. Journal of Venomous Animals and Toxins including Tropical Diseases, 27. ISSN 1678-9199, DOI https://doi.org/10.1590/1678-9199-JVATITD-2021-0051.
Tan, Choo Hock and Palasuberniam, Praneetha and Blanco, Francis Bonn and Tan, Kae Yi (2021) Immunoreactivity and neutralization capacity of Philippine cobra antivenom against Naja philippinensis and Naja samarensis venoms. Transactions of the Royal Society of Tropical Medicine and Hygiene, 115 (1). pp. 78-84. ISSN 0035-9203, DOI https://doi.org/10.1093/trstmh/traa087.
Wong, Kin Ying and Tan, Kae Yi and Tan, Nget Hong and Tan, Choo Hock (2021) A Neurotoxic Snake Venom without Phospholipase A(2): Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus). Toxins, 13 (1). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins13010060.
Tan, Choo Hock and Liew, Jia Lee and Chong, Ho Phin and Tan, Nget Hong (2021) Protein decomplexation and proteomics: A complementary assessment method of the physicochemical purity of antivenom. Biologicals, 69. pp. 22-29. ISSN 1045-1056, DOI https://doi.org/10.1016/j.biologicals.2020.12.004.
Tan, Choo Hock and Tan, Kae Yi (2021) De Novo venom-gland transcriptomics of spine-bellied sea snake (hydrophis curtus) from Penang, Malaysia-next-generation sequencing, functional annotation and toxinological correlation. Toxins, 13 (2). ISSN 2072-6651, DOI https://doi.org/10.3390/toxins13020127.
Wong, Kin Ying and Tan, Kae Yi and Tan, Nget Hong and Tan, Choo Hock (2021) A Neurotoxic Snake Venom without Phospholipase A2: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus). Toxins, 13 (1). p. 60. ISSN 2072-6651, DOI https://doi.org/10.3390/toxins13010060.
Chong, Ho Phin and Tan, Kae Yi and Tan, Choo Hock (2020) Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity, and Cell Death Mechanism. Frontiers in Molecular Biosciences, 7. ISSN 2296889X, DOI https://doi.org/10.3389/fmolb.2020.583587.
Pruksaphon, Kritsada and Tan, Kae Yi and Tan, Choo Hock and Simsiriwong, Pavinee and Gutierrez, Jose Maria and Ratanabanangkoon, Kavi (2020) An in vitro alpha-neurotoxin-nAChR binding assay correlates with lethality and in vivo neutralization of a large number of elapid neurotoxic snake venoms from four continents. PLoS Neglected Tropical Diseases, 14 (8). ISSN 19352727, DOI https://doi.org/10.1371/journal.pntd.0008581.
Tan, Choo Hock and Liew, Jia Lee and Navanesan, Suerialoasan and Sim, Kae Shin and Tan, Nget Hong and Tan, Kae Yi (2020) Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin). Journal of Venomous Animals and Toxins including Tropical Diseases, 26. ISSN 1678-9199, DOI https://doi.org/10.1590/1678-9199-JVATITD-2020-0013.
Tan, Kae Yi and Ng, Tzu Shan and Bourges, Aymeric and Ismail, Ahmad Khaldun and Maharani, Tri and Khomvilai, Sumana and Sitprija, Visith and Tan, Nget Hong and Tan, Choo Hock (2020) Geographical variations in king cobra (Ophiophagus hannah) venom from Thailand, Malaysia, Indonesia and China: On venom lethality, antivenom immunoreactivity and in vivo neutralization. Acta Tropica, 203. p. 105311. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2019.105311.
Tan, Kae Yi and Wong, Kin Ying and Tan, Nget Hong and Tan, Choo Hock (2020) Quantitative proteomics of Naja annulifera (sub-Saharan snouted cobra) venom and neutralization activities of two antivenoms in Africa. International Journal of Biological Macromolecules, 158. pp. 605-616. ISSN 0141-8130, DOI https://doi.org/10.1016/j.ijbiomac.2020.04.173.
Tan, Kae Yi and Tan, Choo Hock (2020) Toward improved antivenom management of snakebite envenomation in Southeast Asia: The Indonesian perspective. Toxicon, 177. S29. ISSN 0041-0101, DOI https://doi.org/10.1016/j.toxicon.2019.12.029.
Ratanabanangkoon, Kavi and Tan, Kae Yi and Pruksaphon, Kritsada and Klinpayom, Chaiya and Gutiérrez, José María and Quraishi, Naeem H. and Tan, Choo Hock (2020) A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms. Scientific Reports, 10 (1). p. 11261. ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-020-66657-8.
Tang, Esther Lai Har and Tan, Nget Hong and Fung, Shin Yee and Tan, Choo Hock (2019) Comparative proteomes, immunoreactivities and neutralization of procoagulant activities of Calloselasma rhodostoma (Malayan pit viper) venoms from four regions in Southeast Asia. Toxicon, 169. pp. 91-102. ISSN 0041-0101, DOI https://doi.org/10.1016/j.toxicon.2019.08.004.
Tan, Choo Hock and Wong, Kin Ying and Tan, Nget Hong and Ng, Tzu Shan and Tan, Kae Yi (2019) Distinctive Distribution of Secretory Phospholipases A2 in the Venoms of Afro-Asian Cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus). Toxins, 11 (2). p. 116. ISSN 2072-6651, DOI https://doi.org/10.3390/toxins11020116.
Tan, Kae Yi and Liew, Sin Teng and Tan, Qian Yi and Abdul-Rahman, Farah Nadhirah and Azmi, Nor Izzati and Sim, Si Mui and Tan, Nget Hong and Khomvilai, Sumana and Sitprija, Visith and Tan, Choo Hock (2019) Evaluating the physicochemical properties and efficacy of recently expired and aged antivenom products from Thailand and Taiwan. Toxicon, 160. pp. 55-58. ISSN 0041-0101, DOI https://doi.org/10.1016/j.toxicon.2019.02.010.
Tan, Choo Hock and Wong, Kin Ying and Chong, Ho Phin and Tan, Nget Hong and Tan, Kae Yi (2019) Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia. Journal of Proteomics, 206. p. 103418. ISSN 1874-3919, DOI https://doi.org/10.1016/j.jprot.2019.103418.
Tan, Kae Yi and Liew, Jia Lee and Tan, Nget Hong and Quah, Evan S.H. and Ismail, Ahmad Khaldun and Tan, Choo Hock (2019) Unlocking the secrets of banded coral snake (Calliophis intestinalis, Malaysia): A venom with proteome novelty, low toxicity and distinct antigenicity. Journal of Proteomics, 192. pp. 246-257. ISSN 1874-3919, DOI https://doi.org/10.1016/j.jprot.2018.09.006.
Oh, Angeline Mei Feng and Tan, Choo Hock and Tan, Kae Yi and Quraishi, Naeem H. and Tan, Nget Hong (2019) Venom proteome of Bungarus sindanus (Sind krait) from Pakistan and in vivo cross-neutralization of toxicity using an Indian polyvalent antivenom. Journal of Proteomics, 193. pp. 243-254. ISSN 1874-3919, DOI https://doi.org/10.1016/j.jprot.2018.10.016.
Tan, Choo Hock and Tan, Kae Yi and Ng, Tzu Shan and Quah, Evan S.H. and Ismail, Ahmad Khaldun and Khomvilai, Sumana and Sitprija, Visith and Tan, Nget Hong (2019) Venomics of Trimeresurus (Popeia) nebularis, the Cameron Highlands Pit Viper from Malaysia: Insights into Venom Proteome, Toxicity and Neutralization of Antivenom. Toxins, 11 (2). p. 95. ISSN 2072-6651, DOI https://doi.org/10.3390/toxins11020095.
Wong, Kin Ying and Tan, Choo Hock and Tan, Kae Yi and Quraishi, Naeem H. and Tan, Nget Hong (2018) Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study. Journal of Proteomics, 175. pp. 156-173. ISSN 1874-3919, DOI https://doi.org/10.1016/j.jprot.2017.12.012.
Faisal, Tasnim and Tan, Kae Yi and Sim, Si Mui and Quraishi, Naeem H. and Tan, Nget Hong and Tan, Choo Hock (2018) Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper ( Daboia russelii ) from the wild. Journal of Proteomics, 183. pp. 1-13. ISSN 1874-3919, DOI https://doi.org/10.1016/j.jprot.2018.05.003.
Tan, Choo Hock and Tan, Kae Yi and Ng, Tzu Shan and Sim, Si Mui and Tan, Nget Hong (2018) Venom Proteome of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia: Toxicity Correlation, Immunoprofiling and Cross-Neutralization by Sea Snake Antivenom. Toxins, 11 (1). p. 3. ISSN 2072-6651, DOI https://doi.org/10.3390/toxins11010003.
Tan, Choo Hock and Tan, Nget Hong and Sim, Si Mui and Fung, Shin Yee and Gnanathasan, Christeine Ariaranee (2012) Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: Antibody production with diagnostic and therapeutic potentials. Acta Tropica, 122 (3). pp. 267-275. ISSN 0001-706X,
Tan, Choo Hock and Leong, Poh Kuan and Fung, Shin Yee and Sim, Si Mui and Ponnudurai, Gnanajothy and Ariaratnam, Christeine and Khomvilai, Sumana and Sitprija, Visith and Tan, Nget Hong (2011) Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model. Acta Tropica, 117 (2). pp. 119-124. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2010.11.001.