The effects of placement and geometry on thermo-pneumatic pumping on centrifugal microfluidic compact disc (CD) platforms

Aeinehvand, Mohammad Mahdi and Moebius, Jacob and Harun, Sulaiman Wadi and Abd Rahman, Noorsaadah and Madou, Marc and Ibrahim, Fatimah (2012) The effects of placement and geometry on thermo-pneumatic pumping on centrifugal microfluidic compact disc (CD) platforms. In: 2012 2nd IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2012, 2012, Langkawi.

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Thermo-pneumatic pumping (TPP) is used to pump fluids on a microfluidic compact disc (CD) to the center of the CD. The expansion of air during heating drives the fluid transfer during TPP. It is easy to fabricate the TPP air chamber and adjoining channel since there are no moving components in their structure and that the thermal energy is supplied to the pump through localized heating equipment. This allows the pumping process even while the disc is rotating. In this report, by changing the shape and placement of the air chamber, we demonstrate that the experimental behavior of the TPP process can be manipulated by the altering heating rate of the air chamber. The placement and geometry of the air expansion chambers affect the rate of transfer during the TPP process. These modifications allow for the customization of the TPP and for a better incorporation onto the microfluidic CD platform, enabling the platform to be more versatile, more complex in functions and countable to be implemented. © 2012 IEEE.

Item Type: Conference or Workshop Item (Paper)
Additional Information: Conference code: 96763 Export Date: 29 January 2014 Source: Scopus Art. No.: 6498201 doi: 10.1109/IECBES.2012.6498201 Language of Original Document: English Correspondence Address: Aeinehvand, M.M.; Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia References: Madou, M., Zoval, J., Jia, G., Kido, H., Kim, J., Kim, N., Lab on CD (2006) Annu. Rev. Biomed. Eng, 8 (1), pp. 601-628; Garcia-Cordero, J.L., Barrett, L.M., Kennedy, R.O., Ricco, A.J., Microfluidic sedimentation cytometer for milk quality and bovine mastitis monitoring (2010) Biomed Microdevices, 12 (6), pp. 1051-1059; Amasia, M., Cozzens, M., Madou, M., Centrifugal microfluidic platform for rapid PCR amplification using integrated thermoelectric heating and ice-valving (2011) Sensors and Actuators B: Chemical; Kong, M.C.R., Salin, E.D., Pneumatically pumping fluids radially inward on centrifugal microfluidic platforms in motion (2010) Anal Chem, 82 (19), pp. 8039-8041; Abi-Samra, K., Clime, L., Kong, L., Gorkin, R., Kim, T.H., Cho, Y.K., Madou, M., Thermo-pneumatic pumping in centrifugal microfluidic platforms (2011) Microfluidics and Nanofluidics, pp. 1-10; Ha, S.M., Cho, W., Ahn, Y., Disposable thermo-pneumatic micropump for bio lab-on-A-chip application (2009) Microelectron Eng, 86 (4-6), pp. 1337-1339; Handique, K., Burke, D.T., Mastrangelo, C.H., Burns, M.A., Onchip thermopneumatic pressure for discrete drop pumping (2001) Anal. Chem, 73 (8), pp. 1831-1838; Song, W.H., Lichtenberg, J., Thermo-pneumatic, single-stroke micropump (2005) J. Micromech. Microeng, 15 (8), pp. 1425-1432 Sponsors: University Malaya; CBMTI University Malaya; Tourism Malaysia; Kumpulan ABEX Sdn Bhd; AMAN kampus
Uncontrolled Keywords: Centrifugal microfluidic platforms; Microfluidic Disc; Poly(methyl methacrylate) thermal absorption; Thermo-pneumatic pumping; Air expansion; Centrifugal microfluidic platform; Centrifugal microfluidics; Fluid transfer; Localized heating; Moving components; Pumping process; Thermal absorptions; Biomedical engineering; Centrifugation; Compact disks; Esters; Microfluidics; Pneumatics
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Faculty of Science > Department of Chemistry
Depositing User: Mr Jenal S
Date Deposited: 12 Feb 2014 01:16
Last Modified: 10 Oct 2018 05:59

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