Bioelectrical impedance analysis device: measurement of bioelectrical tissue conductivity in dengue patients

Abdul Rahim, H. and Taib, M.N. and Ibrahim, F. and Abdul Rahim, Z. (2011) Bioelectrical impedance analysis device: measurement of bioelectrical tissue conductivity in dengue patients. Sensors and Transducers, 125 (2). pp. 256-265. ISSN 17265479 (ISSN),

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This paper describes and introduces a new approach to monitor dengue hemorrhagic fever using BIA technique. This technique is an in vivo technique where an approximately a small average constant current of 460 μA at single frequency, 50 kHz is applied through human body, and measure the body's resistance and reactance to that current via four-surface electrode. These measurements are combined with the patient data (i.e. age, sex, height and weight) to estimate mass and water compartments. The dengue's clinical studies in correlation with the BIA measurement have been conducted on 119 male and 91 female who are the DHF patients in Universiti Kebangsaan Malaysia, Hospital (HUKM) in Malaysia. The data obtained show that it is possible to predict a patient's condition; recovering or leading to hemorrhagic by monitoring the increasing trend of phase angle and reactance and the decreasing trend for the of ratio of extracellular to intracellular water (ECW/ICW) and ratio of extracellular body mass to body cell mass (ECM/BCM). Experimental findings show that bioelectrical tissue conductivity (BETC), as reflected by reactance is the key determinant indicator for monitoring the hemoglobin status in the DHF patients. Hence, this novel approach of BIA technique can provide rapid, non-invasive, and promising method for monitoring and evaluating the status of the DHF patients. © 2011 IFSA.

Item Type: Article
Additional Information: Export Date: 29 January 2014 Source: Scopus Language of Original Document: English Correspondence Address: Abdul Rahim, H.; Department of Control and Instrumentation Engineering, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 UTM Skudai, Johor, Malaysia References: Kyle, U.G., Bosaeus, I., de Lorenzo, A.D., Deurenberg, P., Elia, M., Gomez, J.M., Heitmann, B.L., Pichard, C., Biolectrical impedance analysis - part1: Review of principles and methods (2004) Clinical Nutrition, 23, pp. 1226-1243; Skae, F.M., Dengue fever in Penang (1902) Br. Med. J, 2, pp. 1581-1582; Dengue Fever Studies in Malaysia Institute for Medical Research Malaysia (1986) Bulletion, 23, pp. 1-5. , S. C. Gordon, Dengue: an introduction. In: Rudnick A, Lim TW, Eds; Organization, W.H., (1997) Dengue Haemorrhagic fever Diagnosis, treatment, Prevention, and control, , 2nd ed. WHO, Geneva; (1998) W. C. a. R. Annual Report, Dengue Haemorrhagic Fever, , Dept. of Medical Microbiology, Fac. of Medicine, University of Malaya; Narayanan, N., Aravind, M.A., Ambikapathy, P., Prema, R., Jeyapaul, M.P., Dengue fever-Clinical and laboratory parameters associated with complications (2003) Dengue Bulletin, 27, pp. 108-115; Bethell, D.B., Gamble, J., Loc, P.P., Dung, N.M., Chau, T.T.H., Loan, H.T., Thuy, T.T., Day, N.P.J., Noninvasive measurement of microvascular leakage in patients with dengue hemorhhagic fever (2001) Clin. Infect. Dis., 32, pp. 243-253; Balasubramanian, S., Anandnathan, K., Shivabalan, S., Dutta, M., Amalraj, E., Cut-off haematocrit value for haemoconcentration in dengue haemorrhagic fever (2004) J. Trop. Pediatr, 50, pp. 123-124; Libraty, D.H., Endy, T.P., Kalayanarooj, S., Chansiriwongs, W., Nisalak, A., Green, S., Ennis, F.A., Rothman, A.L., Assessment of body fluid compartment volumes by multifrequency bioelectrical impedance spectroscopy in children with dengue (2002) Transactions of the Royal Society of Tropical Medicine and Hygine, 96, pp. 295-299; Huang, Y.H., Liu, C.C., Wang, S.T., Lei, H.Y., Liu, H.S., Lin, Y.S., Wu, H.L., Yeh, T.M., Activation of coagulation and fibrinolysis during dengue infection (2001) Med. Virol., 63, pp. 247-251; Van-Gorp, E.C., Suharti, C., Mairuhu, A.T., Dolmans, W.M., Ven-Der, V.J., Demacker, P.N., Ven-Der-Meer, J.W., Changes in the plasma lipid profile as potential predictor of clinical outcome in dengue hemorrhagic fever (2002) Clin. Infect. Dis., 34, pp. 1150-1153; Lukaski, H.C., Bolonchuk, W.W., Hall, C.B., Siders, W.A., Validation of tetrapolar bioelectrical impedance method to assess human body composition (1986) Journal of Applied Physiology, 60 (4), pp. 1327-1332; Siler, J.F., Hall, M.W., Hitchens, A., Dengue, its history, epidemiology, mechanism of transmission, etiology, clinical manifestations, immunity and preventation (1926) Philipp. J. Sci, 29, pp. 1-304; Ibrahim, F., Ismail, N.A., Taib, M.N., Wan, A.W.A.B., Modeling of hemoglobin in dengue fever and dengue hemorrhagic fever using biolectrical impedance (2004) Physiol. Meas., 25, pp. 607-615; Berhman, R.E., Kliegman, R.M., (2002) Nelson Essentials of Prediatrics, p. 610. , 4th edition, WB Sauders Company, Philadelphia; Ibrahim, F., (2005) Prognosis of dengue fever and dengue haemorrhagic fever using bioelectrical impedance, , Ph. D. dissertation, Department of Biomedical Engineering, University of Malaya, July; (1997) Dengue Haemorrhagic fever Diagnosis, treatment, Prevention, and control, , 2nd ed., World Health Organization, Geneva; Chungue, E., Boutin, J.P., Roux, J., Antibody capture ELISA for IgM antibody titration in sera for dengue serodiagnosis and survellance (1989) Research in Virology, 140, pp. 229-240; Herlina, A.R., Fatimah, I., Mohd, N.T., A non-invasive system for predicting hemoglobin (Hb) in dengue fever (DF) and dengue hemorrhagic fever (DHF) (2005) Proc. Int. Conf. on Sensor and New Techniques in Pharmaceutical and Biomedical Research (ASIASENSE), , in, Kuala Lumpur; Abdul, R.H., Ibrahim, F., Taib, M.N., Modelling of hemoglobin in dengue infection application (2006) Journal of Electrical Engineering (ELEKTRIKA), 8, pp. 64-67
Uncontrolled Keywords: Bioelectrical impedance analysis device, Bioelectrical tissue conductivity, Dengue fever, Dengue haemorrhagic fever, Haematological profile, Bioelectrical impedance analysis, Dengue haemorrhagic fevers, Electric impedance, Enzyme activity, Hospital data processing, Tissue, Monitoring
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 12 Feb 2014 01:22
Last Modified: 01 Nov 2017 05:50

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