Effect of spatial inlet velocity profiles on the vortex formation pattern in a dilated left ventricle

Chan, B.T. and Lim, Einly and Ong, C.W. and Abu Osman, Noor Azuan (2015) Effect of spatial inlet velocity profiles on the vortex formation pattern in a dilated left ventricle. Computer Methods in Biomechanics and Biomedical Engineering, 18 (1). pp. 90-96. ISSN 1025-5842, DOI https://doi.org/10.1080/10255842.2013.779683.

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Despite the advancement of cardiac imaging technologies, these have traditionally been limited to global geometrical measurements. Computational fluid dynamics (CFD) has emerged as a reliable tool that provides flow ?eld information and other variables essential for the assessment of the cardiac function. Extensive studies have shown that vortex formation and propagation during the filling phase acts as a promising indicator for the diagnosis of the cardiac health condition. Proper setting of the boundary conditions is crucial in a CFD study as they are important determinants, that affect the simulation results. In this article, the effect of different transmitral velocity profiles (parabolic and uniform profile) on the vortex formation patterns during diastole was studied in a ventricle with dilated cardiomyopathy (DCM). The resulting vortex evolution pattern using the uniform inlet velocity profile agreed with that reported in the literature, which revealed an increase in thrombus risk in a ventricle with DCM. However the application of a parabolic velocity profile at the inlet yields a deviated vortical flow pattern and overestimates the propagation velocity of the vortex ring towards the apex of the ventricle. This study highlighted that uniform inlet velocity profile should be applied in the study of the filling dynamics in a left ventricle because it produces results closer to that observed experimentally.

Item Type: Article
Funders: UM/MOHE HIR UM.C/HIR/MOHE/ENG/14 D000014-16001
Additional Information: Chan, Bee Ting Lim, Einly Ong, Chi Wei Abu Osman, Noor Azuan eng Research Support, Non-U.S. Gov't England 2013/03/26 06:00 Comput Methods Biomech Biomed Engin. 2015;18(1):90-6. doi: 10.1080/10255842.2013.779683. Epub 2013 Mar 22.
Uncontrolled Keywords: Computational fluid dynamics, velocity profile, vortex; dilated cardiomyopathy
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 29 Jul 2015 03:18
Last Modified: 07 Feb 2019 07:39
URI: http://eprints.um.edu.my/id/eprint/13825

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