Reexamination of risk criteria in dengue patients using the self-organizing map

Faisal, T. and Taib, M.N. and Ibrahim, F. (2010) Reexamination of risk criteria in dengue patients using the self-organizing map. Medical and Biological Engineering and Computing, 48 (3). pp. 293-301. ISSN 0140-0118, DOI https://doi.org/10.1007/s11517-009-0561-x.

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Abstract

Even though the World Health Organization criteria's for classifying the dengue infection have been used for long time, recent studies declare that several difficulties have been faced by the clinicians to apply these criteria. Accordingly, many studies have proposed modified criteria to identify the risk in dengue patients based on statistical analysis techniques. None of these studies utilized the powerfulness of the self-organized map (SOM) in visualizing, understanding, and exploring the complexity in multivariable data. Therefore, this study utilized the clustering of the SOM technique to identify the risk criteria in 195 dengue patients. The new risk criteria were defined as: platelet count less than or equal 40,000 cells per mm 3, hematocrit concentration great than or equal 25 and aspartate aminotransferase (AST) rose by fivefold the normal upper limit for AST/alanine aminotransfansferase (ALT) rose by fivefold the normal upper limit for ALT. The clusters analysis indicated that any dengue patient fulfills any two of the risk criteria is consider as high risk dengue patient. © 2009 International Federation for Medical and Biological Engineering.

Item Type: Article
Funders: UNSPECIFIED
Additional Information: Faisal, Tarig Taib, Mohd Nasir Ibrahim, Fatimah eng Research Support, Non-U.S. Gov't 2009/12/18 06:00 Med Biol Eng Comput. 2010 Mar;48(3):293-301. doi: 10.1007/s11517-009-0561-x. Epub 2009 Dec 17.
Uncontrolled Keywords: Clustering, Dengue fever, Risk criteria, Self-organizing ma, World Health Organization, Aspartate aminotransferase, Multi variables, Self-organized map, Statistical analysis, Upper limits, Cluster analysis, Conformal mapping, Health, Strength of materials, Health risks
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 02 Apr 2014 01:33
Last Modified: 01 Nov 2017 05:47
URI: http://eprints.um.edu.my/id/eprint/9343

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