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Nallappan, Devi and Ong, Kien Chai and Palanisamy, Uma Devi and Chua, Kek Heng and Kuppusamy, Umah Rani (2023) Myricetin derivative-rich fraction from Syzygium malaccenseprevents high-fat diet-induced obesity, glucose intolerance and oxidative stress in C57BL/6J mice. Archives of Physiology and Biochemistry, 129 (1). pp. 186-197. ISSN 1381-3455, DOI https://doi.org/10.1080/13813455.2020.1808019.
Subramaniam, Sarasvathy and Ong, Kien Chai and Sabaratnam, Vikineswary and Chua, Kek Heng and Kuppusamy, Umah Rani (2023) The medicinal mushroom Ganoderma neo-japonicum (Agaricomycetes) polysaccharide extract prevents obesity-induced diabetes in C57BL/6J mice. International Journal of Medicinal Mushrooms, 25 (4). pp. 27-42. ISSN 1521-9437, DOI https://doi.org/10.1615/IntJMedMushrooms.2023047595.
Ong, Kien Chai and Ng, Khong Ying and Ng, Chiu Wan and Tan, Soon Hao and Teo, Woon Li and Karim, Norain and Kumar, Shalini and Wong, Kum Thong (2022) Neuronal infection is a major pathogenetic mechanism and cause of fatalities in human acute Nipah virus encephalitis. Neuropathology and Applied Neurobiology, 48 (6). ISSN 0309-0167,
Lalani, Salima and Tan, Soon Hao and Tan, Kuan Onn and Lim, Hui Xuan and Ong, Kien Chai and Wong, Kum Thong and Poh, Chit Laa (2021) Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice. Life Sciences, 287. ISSN 0024-3205, DOI https://doi.org/10.1016/j.lfs.2021.120097.
Mahendran, Rhubaniya and Lim, Soo Kun and Ong, Kien Chai and Chua, Kek Heng and Chai, Hwa Chia (2021) Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment. Clinical and Experimental Nephrology, 25 (11). pp. 1163-1172. ISSN 1342-1751, DOI https://doi.org/10.1007/s10157-021-02111-x.
Ang, W. X. and Sarasvathy, S. and Kuppusamy, Umah Rani and Sabaratnam, Vikineswary and Tan, S. H. and Wong, Kum Thong and Perera, D. and Ong, Kien Chai (2021) In vitro antiviral activity of medicinal mushroom Ganoderma neo-japonicum Imazeki against enteroviruses that caused hand, foot and mouth disease. Tropical Biomedicine, 38 (3). pp. 239-247. ISSN 0127-5720, DOI https://doi.org/10.47665/tb.38.3.063.
Nallappan, Devi and Chua, Kek Heng and Ong, Kien Chai and Chong, Chun Wie and Teh, Cindy Shuan Ju and Palanisamy, Uma Devi and Kuppusamy, Umah Rani (2021) Amelioration of high-fat diet-induced obesity and its associated complications by a myricetin derivative-rich fraction from Syzygium malaccense in C57BL/6J mice. Food & Function, 12 (13). pp. 5876-5891. ISSN 2042-6496, DOI https://doi.org/10.1039/d1fo00539a.
Lee, Michelle Hui Pheng and Tan, Chee Wah and Tee, Han Kang and Ong, Kien Chai and Sam, I-Ching and Chan, Yoke Fun (2021) Vaccine candidates generated by codon and codon pair deoptimization of enterovirus A71 protect against lethal challenge in mice. Vaccine, 39 (12). pp. 1708-1720. ISSN 0264-410X, DOI https://doi.org/10.1016/j.vaccine.2021.02.024.
Udos, Waldo and Ooi, Cheong-Weng and Tan, Soon-Hao and Lim, Kok-Sing and Ee, Yen Jie and Ong, Kien Chai and Ahmad, Harith (2021) Label-free surface-plasmon resonance fiber grating biosensor for Hand-foot-mouth disease (EV-A71) detection. Optik, 228. ISSN 0030-4026, DOI https://doi.org/10.1016/j.ijleo.2020.166221.
Yu, Shu Pin and Ong, Kien Chai and Tan, Soon Hao and Perera, David and Wong, Kum Thong (2020) Japanese encephalitis virus: Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model. Neurology Asia, 25 (3). pp. 279-284. ISSN 1823-6138,
Yee, Pinn Tsin Isabel and Tan, Soon Hao and Ong, Kien Chai and Tan, Kuan Onn and Wong, Kum Thong and Hassan, Sharifah Syed and Poh, Chit Laa (2019) Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice. Scientific Reports, 9 (1). p. 4805. ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-019-41285-z.
Shimizu, Hiroyuki and Tee, Han Kang and Tan, Chee Wah and Yogarajah, Thinesshwary and Lee, Michelle Hui Pheng and Chai, Hann Juang and Hanapi, Nur Aziah and Yusof, Siti R. and Ong, Kien Chai and Lee, Vannajan Sanghiran and Sam, I-Ching and Chan, Yoke Fun (2019) Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive enterovirus A71 virulence in mice. PLoS Pathogens, 15 (11). e1007863. ISSN 1553-7374, DOI https://doi.org/10.1371/journal.ppat.1007863.
Yu, Shu Pin and Ong, Kien Chai and Perera, David and Wong, Kum Thong (2019) Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5. Virology, 527. pp. 107-115. ISSN 0042-6822, DOI https://doi.org/10.1016/j.virol.2018.10.015.
Tan, Jia Shin Jessica and Ong, Kien Chai and Ong, Diana Bee Lan and Razack, Azad and Lim, Jasmine and Yunus, Rosna and Sundram, Murali and Rhodes, Anthony (2018) Heterogenous expression of ERG oncoprotein in Malaysian men with adenocarcinoma of the prostate. Malaysian Journal of Pathology, 40 (2). pp. 103-110. ISSN 0126-8635,
Nik Nadia, Nik Mohd Nasir and Tan, Chee Wah and Ong, Kien Chai and Sam, I-Ching and Chan, Yoke Fun (2018) Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71. Journal of Medical Virology, 90 (6). pp. 1164-1167. ISSN 0146-6615, DOI https://doi.org/10.1002/jmv.25061.
Yogarajah, T. and Ong, Kien Chai and Perera, D. and Wong, Kum Thong (2017) AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication. Scientific Reports, 7 (1). p. 5845. ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-017-05589-2.
Yogarajah, T. and Ong, Kien Chai and Perera, D. and Wong, Kum Thong (2017) Enterovirus A71 and coxsackievirus A16 show different replication kinetics in human neuronal and non-neuronal cell lines. Archives of Virology, 162 (3). pp. 727-737. ISSN 0304-8608, DOI https://doi.org/10.1007/s00705-016-3157-4.
Jindal, H.M. and Zandi, K. and Ong, Kien Chai and Velayuthan, Rukumani Devi and Rasid, S.M. and Samudi, Chandramathi and Sekaran, Shamala Devi (2017) Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PeerJ, 5 (10). e3887. ISSN 2167-8359, DOI https://doi.org/10.7717/peerj.3887.
Yogarajah, Thinesshwary and Ong, Kien Chai and Perera, David and Wong, Kum Thong (2017) RSAD2 and AIM2 Modulate Coxsackievirus A16 and Enterovirus A71 Replication in Neuronal Cells in Different Ways That May Be Associated with Their 5′ Nontranslated Regions. Journal of Virology, 92 (6). e01914-17. ISSN 0022-538X, DOI https://doi.org/10.1128/JVI.01914-17.
Phyu, W.K. and Ong, Kien Chai and Kong, C.K. and Khalil, A.A. and Ramanujam, T.M. and Wong, Kum Thong (2017) Squamous epitheliotropism of Enterovirus A71 in human epidermis and oral mucosa. Scientific Reports, 7 (1). p. 45069. ISSN 2045-2322, DOI https://doi.org/10.1038/srep45069.
Thanh, T.T. and Anh, N.T. and Tham, N.T. and Van, H.M.T. and Sabanathan, S. and Qui, P.T. and Ngan, T.T. and Van, T.T.M. and Nguyet, L.A. and Ny, N.T.H. and Thanh, L.T.M. and Ong, Kien Chai and Perera, D. and Viet, D.C. and Khanh, T.H. and Ha, D.Q. and Tuan, H.M. and Wong, Kum Thong and Hung, N.T. and Chau, N.V.V. and Thwaites, G. and van Doorn, H.R. and Van Tan, L. (2015) Validation and utilization of an internally controlled multiplex Real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus A71 associated with hand foot and mouth disease. Virology Journal, 12 (1). p. 85. ISSN 1743-422X, DOI https://doi.org/10.1186/s12985-015-0316-2.
