MycoCAP - Mycobacterium Comparative Analysis Platform

Choo, S.W. and Ang, M.Y. and Dutta, A. and Tan, S.Y. and Siow, C.C. and Heydari, H. and Mutha, N.V.R. and Wee, W.Y. and Wong, G.J. (2015) MycoCAP - Mycobacterium Comparative Analysis Platform. Scientific Reports, 5. ISSN 2045-2322,

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Official URL: DOI: 10.1038/srep18227


Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp. With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL:

Item Type: Article
Uncontrolled Keywords: Bacterial Virulence Factors; Genomic Island Discovery; Sequence-Analysis; Database; Identification;Alignment; Visualization; Circos; Vfdb; Abscessus
Subjects: Q Science > Q Science (General)
T Technology > T Technology (General)
Depositing User: Mrs. Siti Mawarni Salim
Date Deposited: 29 Jul 2016 07:23
Last Modified: 29 Jul 2016 07:23

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