Does lower lean body mass mediate the relationship between falls and higher body mass index in Asian older persons?

Kioh, Sheng H. and Mat, Sumaiyah and Kamaruzzaman, Shahrul Bahyah and Ibrahim, Fatimah and Mohktar, Mas Sahidayana and Hairi, Noran Naqiah and Cumming, Robert G. and Myint, Phyo K. and Tan, Maw Pin (2020) Does lower lean body mass mediate the relationship between falls and higher body mass index in Asian older persons? Journal of Aging and Physical Activity, 28 (3). pp. 426-433. ISSN 1063-8652, DOI https://doi.org/10.1123/JAPA.2019-0011.

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Abstract

The current evidence on the relationship between a higher body mass index (BMI) and falls in older adults is conflicting. This study, therefore, evaluated the relationship between BMI and falls and explored underlying mechanisms for this relationship. Data from 1,340 individuals from the Malaysian Elders Longitudinal Research study, obtained through home-based computer-assisted interviews and followed by hospital-based health checks, were utilized. A history of the presence of falls in the previous 12 months was obtained. The presence of at least one fall in the past 12 months was associated with a higher BMI (odds ratio = 1.03, 95% confidence interval 1.01, 1.06]). The relationship between a higher BMI and falls was, however, attenuated by a lower percentage of lean body mass, which accounted for 69% of the total effect of BMI on the risk of falls. Future studies should now investigate this aforementioned relationship prospectively.

Item Type: Article
Funders: Universiti Malaya [Grant no. GC002A-HTM]
Uncontrolled Keywords: Accidental falls; Aged; Muscle mass; Obesity; Sarcopenia
Subjects: R Medicine > R Medicine (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering > Department of Biomedical Engineering
Faculty of Medicine > Medicine Department
Faculty of Medicine > Social & Preventive Medicine
Depositing User: Ms Zaharah Ramly
Date Deposited: 04 Jun 2025 07:40
Last Modified: 04 Jun 2025 07:40
URI: http://eprints.um.edu.my/id/eprint/36656

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