Zaman, Wan Safwani Wan Kamarul and Nurul, Asma Abdullah and Nordin, Fazlina (2021) Stem cells and cancer stem cells: The Jekyll and Hyde Scenario and their implications in stem cell therapy. Biomedicines, 9 (9). ISSN 2227-9059, DOI https://doi.org/10.3390/biomedicines9091245.
Full text not available from this repository.Abstract
``Jekyll and Hyde'' refers to persons with an unpredictably dual personality, who are battling between good and evil within themselves In this regard, even cells consist of good and evil counterparts. Normal stem cells (NSCs) and cancer stem cells (CSCs) are two types of cells that share some similar characteristics but have distinct functions that play a major role in physiological and pathophysiological development. In reality, NSCs such as the adult and embryonic stem cells, are the good cells and the ultimate treatment used in cell therapy. CSCs are the corrupted cells that are a subpopulation of cancer cells within the cancer microenvironment that grow into a massive tumour or malignancy that needs to be treated. Hence, understanding the connection between NSCs and CSCs is important not just in cancer development but also in their therapeutic implication, which is the focus of this review.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya Research University (RU) Grant-Faculty Program (Faculty of Engineering) (GPF039A-2019) |
| Uncontrolled Keywords: | Stem cells; Stem cell therapy; Cancer stem cells; Cancer cell; Biosafety; Bioefficacy |
| Subjects: | T Technology > TA Engineering (General). Civil engineering (General) T Technology > TP Chemical technology |
| Divisions: | Faculty of Engineering |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 11 May 2022 07:13 |
| Last Modified: | 11 May 2022 07:13 |
| URI: | http://eprints.um.edu.my/id/eprint/26970 |
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