Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches

Nour, Shirin and Imani, Rana and Chaudhry, G. Rasul and Sharifi, Ali Mohammad (2021) Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches. Journal of Biomedical Materials Research Part A, 109 (4). pp. 453-478. ISSN 1549-3296, DOI https://doi.org/10.1002/jbm.a.37105.

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Abstract

Skin injuries and in particular, chronic wounds, are one of the major prevalent medical problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration, impaired angiogenesis can cause several complications during the wound healing process and skin regeneration. Therefore, induction or promotion of angiogenesis can be considered as a promising approach to accelerate wound healing. This article presents a comprehensive overview of current and emerging angiogenesis induction methods applied in several studies for skin regeneration, which are classified into the cell, growth factor, scaffold, and biological/chemical compound-based strategies. In addition, the advantages and disadvantages of these angiogenic strategies along with related research examples are discussed in order to demonstrate their potential in the treatment of wounds.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Angiogenesis; Biomaterials; Chronic wound; Skin tissue engineering; Wound healing
Subjects: R Medicine > R Medicine (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 13 Apr 2022 07:38
Last Modified: 13 Apr 2022 07:38
URI: http://eprints.um.edu.my/id/eprint/26700

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