Evaluation of pressure changes for capillary and fishbone valves in Lab-on-CD systems

Peyman, J. and Akbar Nozari, A. and Soin, N. and Ibrahim, F. (2009) Evaluation of pressure changes for capillary and fishbone valves in Lab-on-CD systems. In: International Conference for Technical Postgraduates 2009, TECHPOS 2009, 2009, Kuala Lumpur.

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Abstract

This paper describes an investigation in Capillary and Fishbone valves as controlling medium of liquid flow for microdevices and diagnosis methods like Enzymed Linked Immonusorbent Assays (ELISA). Numerical simulation by MATLAB programming was employed to predict the pressure gradient at the Capillary valve expansion part and Fishbone valve section. The analysis results of pressure gradient versus channel width values depicted that an increase in the width of channel leads to a decrease in the pressure gradient. While an increase in Surface tension raises up the required pressure gradient for both valves. Pressure gradient sensitivity to contact angle between liquid and gas in the Capillary valve is more than the Fishbone valve.

Item Type: Conference or Workshop Item (Paper)
Additional Information: Conference code: 79876 Export Date: 29 January 2014 Source: Scopus Art. No.: 5412057 doi: 10.1109/TECHPOS.2009.5412057 Language of Original Document: English Correspondence Address: Peyman, J.; Dept. of Electrical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia References: Silva, G., Leal, N., Semiao, V., (2009) Critical Pressure for Capillary Valves in A Lab-On-a-Disk: CFD and Flow Visualization; Steigert, J., Grumann, M., Brenner, T., Mittenbuhler, K., Nann, T., Ruhe, J., Moser, I., Ducree, T., (2005) Integrated Sample Preparation, Reaction and Detection on A High-frequency Centrifugal Microfluidic Platform, , October; Zoval, J.V., Madou, M.J., Fundamental of Microfabrication, Centrifuge Based Fluidic Platforms; He, H., Yuan, Y., Wang, W., Chiou, N.-R., Jepstein, A., Lee, J., (2009) Design and Testing of A Microfluidic Biochip for Cytokine Enzyme-linked Immunosorbent Assay; Cho, H., Kim, H.-Y., Kang, J.Y., Kim, T.S., (2006) How the Capillary Burst Microvalve Works; Lu, C., Xie, Y., Yang, Y., Cheng, M.M.C., Koh, C.G., Bai, Y., Lee, J., Juang, Y.J., (2007) New Valve and Bonding Designs for Microfluidic Biochips Containing Proteins; Kim, J., Kido, H., Rangel, R.H., Madou, M.J., (2007) Passive Flow Switching Valves on A Centrifugal Microfluidic Platform; Liu, M., Zhang, J., Liu, Y., Lau, W.M., Yang, J., (2008) Modeling of Flow Burst, Flow Timing in Lab-On-a-CD Systems and Its Application in Digital Chemical Analysis; Gliere, A., Delattre, C., (2006) Modeling and Fabrication of Capillary Stop Valves for Planar Microfluidic Systems; Chew, M., Teo, W., Xie, L., Premachandran, C.S., Wong, W.H., Xu, D., Yao, Q., (2006) Study of A Capillary Force Driven Passive Valve for A Microfluidic Package; Lai, S., Wang, S., Luo, J., James Lee, L., Yang, S.-T., Madou, M.J., (2004) Design of A Compact Dist-like Microfluidic Platform for Enzyme-Linked Immunosorbent Assay; Chen, J.M., Huang, P.-C., Lin, M.-G., (2007) Analysis and Experiment of Capillary Valves for Micro- Fluidics on A Rotating Disk; Messinger, R.J., (2006) Micro-fluidics: Mathematical Modeling and Empirical Analysis of the Burst Frequencies of A Novel Fishbone Capillary Valve and the Development of An Algorithm to Calculate Its Theoretical Hold Time
Uncontrolled Keywords: Analysis results, Channel widths, Diagnosis methods, Liquid flow, Matlab programming, Micro devices, Numerical simulation, Pressure change, Computer simulation, Contact angle, Liquids, MATLAB, Pressure gradient, Surface tension, Valves (mechanical)
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 24 Mar 2014 03:34
Last Modified: 01 Nov 2017 04:06
URI: http://eprints.um.edu.my/id/eprint/9295

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