Subramaniam, Reasmyraj R. and Syafiq, Amirul and Balakrishnan, Vengadaesvaran and Ahmad, Muhammad Shakeel and Abd Rahim, Nasrudin and Hassandarvish, Pouya (2024) A study on influence of wettability on antiviral coating using polyethylene glycol (PEG) and acrylic binder. Journal of Polymer Engineering, 44 (4). pp. 291-298. ISSN 0334-6447, DOI https://doi.org/10.1515/polyeng-2023-0263.
Full text not available from this repository.Abstract
One of the biggest problems facing medical science today is preventing viral outbreaks, which highlights the significance of research initiatives aimed at creating antimicrobial coatings for a range of products, including textiles, medical devices, and public spaces. In this study, we aimed to determine the possible antiviral effects of polyethylene glycol (PEG) coating on feline coronavirus (FCoV). The PEG coatings were synthesized by a simple mixing method with a water-based acrylic binder in different weight percentages (3, 5, 10, 15, 20, and 25 wt%). The Spearman-Karber technique was used to calculate the viral titers, which were then expressed as the tissue culture infectious dose at 50 % CPE (TCID50/ml). 20 wt% PEG could result in a 3 log(10) reduction in virus titer with an inhibition rate of approximately 99.9 % against FCoV. The increment of PEG weight percent from 0 to 25 wt% decreases the hardness and glass transition temperature of the coatings from 38.1 to 5.5 HV and 15.45 to -15.48 degrees C. Apart from that, the wettability analysis has revealed that PEG coating is hydrophilic with water contact angle (WCA) of around 75 +/- 0.5 degrees-85 +/- 0.5 degrees. Adding 25 wt% of PEG makes the coating to be superhydrophilic with WCA of 39.85 +/- 0.5 degrees.
| Item Type: | Article |
|---|---|
| Funders: | UM Power Energy-Dedicated Advanced Centre (UMPEDAC), Higher Institution of Excellence (HICoE) Program Research Grant |
| Uncontrolled Keywords: | antiviral; PEG; wettability; coating; biopolymer |
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) T Technology > T Technology (General) T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre Deputy Vice Chancellor (Research & Innovation) Office > UM Power Energy Dedicated Advanced Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 22 Oct 2024 03:42 |
| Last Modified: | 22 Oct 2024 03:42 |
| URI: | http://eprints.um.edu.my/id/eprint/45447 |
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