Tumour seeding following percutaneous needle biopsy of hepatocellular carcinoma

Qua, C.S. and Wong, C.H. and Goh, K.L. (2008) Tumour seeding following percutaneous needle biopsy of hepatocellular carcinoma. Singapore Medical Journal, 49 (1). e8-11. ISSN 0037-5675, DOI 18204759.

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/18204759


We report a hepatocellular carcinoma seeding following needle biopsy in a 57-year-old man who first presented with a focal hepatic lesion at another hospital. The patient had been a hepatitis B carrier for 20 years. Initial surveillance ultrasonography showed a lesion in segment IV, in the background of non-cirrhotic liver and normal serum alpha-foetoprotein level (8 ng/ml). A percutaneous needle biopsy was done and histopathology confirmed well-differentiated hepatocellular carcinoma. The patient had refused surgery and preferred to try traditional medicine. He presented to us four months after the initial biopsy with epigastric swelling. This was found to be due to a tumour seeding along the previous biopsy tract. He was given radiofrequency ablation (RFA) of tumour along the needle tract, in addition to the primary tumour. We conclude that the need for percutaneous needle biopsy should be critically evaluated in patients presenting with focal hepatic lesions and the role of RFA in treating tumour seeding needs further evaluation.

Item Type: Article
Additional Information: Division of Gastroenterology, Department of Medicine, University of Malaya, Lembah Pantai, Kuala Lumpur 50503, Malaysia.
Uncontrolled Keywords: Cancer
Subjects: R Medicine > RD Surgery
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 23 Apr 2011 02:12
Last Modified: 14 Jan 2019 01:33
URI: http://eprints.um.edu.my/id/eprint/970

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