Enterovirus 71 in Malaysia: A decade later

Chan, Yoke Fun and Sam, I.C. and Wee, K.L. and AbuBakar, Sazaly (2011) Enterovirus 71 in Malaysia: A decade later. Neurology Asia, 16 (1). pp. 1-15. ISSN 1823-6138,

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In the last decade, Malaysia has experienced several hand, foot and mouth disease (HFMD) epidemics, complicated by fatalities due to severe neurological involvement. Enterovirus 71 (EV-71) has been implicated as the major causative agent for these epidemics. EV-71 infection is a global public health problem with pandemic potential. In many parts of Asia-Pacific, the virus has emerged as one of the most deadly virus infections amongst young children. The virus is highly transmissible through faecal-oral route and respiratory droplets. A recent rise in neurological complications and deaths suggests that the viruses currently circulating may be more virulent. The major risk factor associated with more severe EV-71 infection is young age and poor cellular immunity. Rapid laboratory diagnosis and molecular surveillance is important to closely monitor the emergence of new EV-71 subgenotypes. Since vaccine and anti-virals for EV-71 are not available, control and prevention strategies remain the only ways to combat the infection.

Item Type: Article
Additional Information: Times Cited: 4 Chan, Yoke-Fun Sam, I-Ching Wee, Kai-Li Abubakar, Sazaly
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms azrahani halim
Date Deposited: 15 Jul 2013 05:04
Last Modified: 13 Feb 2019 08:38
URI: http://eprints.um.edu.my/id/eprint/7327

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