Dietary pattern and oral cancer risk - a factor analysis study

Helen-Ng, L.C. and Razak, I.A. and Ghani, W.M.N. and Marhazlinda, J. and Norain, A.T. and Jallaludin, R.L.R. and Rahman, Z.A.A. and Abdullah, N. and Zain, R.B. (2012) Dietary pattern and oral cancer risk - a factor analysis study. Community Dentistry and Oral Epidemiology, 40 (6). pp. 560-566. ISSN 0301-5661, DOI


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Objectives The role of diet in cancer risk has mainly been investigated based on intake of individual food items. However, food consumption is made up of a combination of various food items. This study aims to determine the association of dietary patterns with oral cancer risk. Methods A total of 306 matched cases and controls were recruited in this study. Data on dietary intake were obtained using food frequency questionnaire (FFQ). Factor analysis (FA) was performed to identify dietary patterns based on the intake of nine major food groups, resulting in four factors/components being retained. The odds ratio (OR) was computed for each component using conditional logistic regression. Results The first pattern labelled as modern was loaded with processed foods and snacks, whereas the second pattern termed as prudent was characterized by intake of fruits and vegetables. The third pattern labelled as traditional consisted of beverages and starches, while the fourth pattern termed as combination was loaded with intakes of dairy, fermented/salted and meat/by-products. A significant reduced risk was found for prudent (OR 0.53, 95 CI = 0.280.98), whereas an increased risk was found for both combination (OR 2.43, 95 CI = 1.334.45) and traditional (OR 2.32, 95 CI = 1.234.25) patterns. However, after adjusting for risk habits of tobacco smoking, alcohol consumption and betel quid chewing, only combination (aOR 2.99, 95 CI = 1.555.75) and traditional (aOR 2.08, 95 CI = 1.093.97) patterns remained significant. Conclusion Consumption in the highest tertile of traditional and combination patterns may induce twice and thrice the risk of oral cancer, respectively.

Item Type: Article
Additional Information: ISI Document Delivery No.: 041FI Times Cited: 0 Cited Reference Count: 39 Cited References: Amtha R, 2009, ORAL ONCOL, V45, pE49, DOI 10.1016/j.oraloncology.2009.01.007 Donaldson Michael S, 2004, Nutr J, V3, P19, DOI 10.1186/1475-2891-3-19 Franceschi S, 1999, CANCER CAUSE CONTROL, V10, P439, DOI 10.1023/A:1008918104757 Gallus S, 2006, CANCER CAUSE CONTROL, V17, P429, DOI 10.1007/s10552-005-0423-2 Garavello W, 2008, EUR J NUTR, V47, P280, DOI 10.1007/s00394-008-0722-y Greenwald P, 2001, EUR J CANCER, V37, P948, DOI 10.1016/S0959-8049(01)00070-3 Grosvenor MB, 2002, NUTR SCI LIFE, P664 Hu FB, 1999, AM J CLIN NUTR, V69, P243 Kreimer AR, 2006, INT J CANCER, V118, P2293, DOI 10.1002/ijc.21577 Levi F, 1998, INT J CANCER, V77, P705, DOI 10.1002/(SICI)1097-0215(19980831)77:5<705::AID-IJC8>3.3.CO;2-Z Levi F, 2000, EUR J CLIN NUTR, V54, P487, DOI 10.1038/sj.ejcn.1601043 Lucenteforte E, 2009, ORAL ONCOL, V45, P461, DOI 10.1016/j.oraloncology.2008.09.002 MACFARLANE GJ, 1995, ORAL ONCOL, V31B, P181 Marchioni Dirce Maria Lobo, 2005, Sao Paulo Med J, V123, P124, DOI 10.1590/S1516-31802005000300007 Marchioni DML, 2007, REV SAUDE PUBL, V41, P19 Northstone K, 2008, EUR J CLIN NUTR, V62, P931, DOI 10.1038/sj.ejcn.1602789 Omar ZA, 2006, MALAYSIAN CANC STAT Pallant J, 2005, SPSS SURVIVAL MANUAL, P172 Parkin DM, 2001, EUR J CANCER, V37, pS4 Peat J, 2001, HLTH SCI RES HDB QUA Petridou E, 2002, CANCER, V94, P2981, DOI 10.1002/cncr.10560 Riboli E., 2003, AM J CLIN NUTR, V78, P559 Sakagami H, 2010, ASIAN PACIFIC ORG CA, P222 Schulze MB, 2001, BRIT J NUTR, V85, P363, DOI 10.1079/BJN2000254 Soler M, 2001, INT J CANCER, V91, P283, DOI 10.1002/1097-0215(200002)9999:9999<::AID-IJC1047>3.0.CO;2-I Stefani ED, 2008, LUNG CANCER, V61, P283 Steinmetz KA, 1996, J AM DIET ASSOC, V96, P1027, DOI 10.1016/S0002-8223(96)00273-8 Stewart BW, 2003, WORLD CANC REPORT Taghavi N, 2007, ARCH IRAN MED, V10, P227 Tee ES, 2000, NUTR COMPOSITION MAL Toledo Ana Lucia Araujo de, 2010, Cad Saude Publica, V26, P135, DOI 10.1590/S0102-311X2010000100014 Toporcov TN, 2004, ORAL ONCOL, V40, P925, DOI 10.1016/j.oraloncology.2004.04.007 Vecchia CL, 2001, EUR J NUTR, V40, P261 Vecchia CL, 1991, INT J EPIDEMIOL, V20, P39 Wunsch V, 2002, ORAL ONCOL, V38, P737, DOI 10.1016/S1368-8375(02)00066-0 Yap S, 2011, SUN MONDAY 0516, P19 Zain RB, 1997, COMMUNITY DENT ORAL, V25, P377, DOI 10.1111/j.1600-0528.1997.tb00959.x Zain RB, 2001, ORAL ONCOL, V37, P205, DOI 10.1016/S1368-8375(00)00133-0 ZHENG TZ, 1993, ORAL ONCOL, V29B, P45 Helen-Ng, Lee Ching Razak, Ishak A. Ghani, Wan Maria Nabillah Marhazlinda, Jamaluddin Norain, Abdul Talib Jallaludin, Raja-Latifah Raja Rahman, Zainal Ariff Abdul Abdullah, Norlida Zain, Rosnah B. Ministry Of Science and Technology and Innovation (MOSTI), Malaysia 06-02-03-0174 PR 0054/05-05; University of Malaya PS171/2010B This study was supported by the research grants from Ministry Of Science and Technology and Innovation (MOSTI), Malaysia (No: 06-02-03-0174 PR 0054/05-05) and Post Graduate Research Fund (PPP), University of Malaya (No: PS171/2010B). We would like to thank all research clerks from Dental Faculty, Universiti Malaya (UM), Universiti Sains Malaysia (USM), Universiti Kebangsaan Malaysia (UKM) and the Ministry of Health, Malaysia Specialist Clinic at General Hospital of Kuala Lumpur, Klang (Selangor), Ipoh (Perak) and Kota Bahru (Kelantan), Sarawak and Sabah for their involvement in data collection. Wiley-blackwell Hoboken
Uncontrolled Keywords: Dietary patterns factor analysis oral cancer pharyngeal cancer energy-intake food groups prevention esophageal brazil
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 19 Apr 2013 00:03
Last Modified: 19 Apr 2013 00:03

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