Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia

Hashim, Syaza Ahmad and Shameli, Kamyar and Md Akhir, Fazreena Nadia and Salleh, Madihah Md and Ismail, Norliana and Hassan, Noraryana and Hara, Hirofumi and Mohamad, Edzrol Niza and Mohamad, Shaza Eva (2022) Identification of flavour chemicals and potentially harmful compounds in refill e-liquids sold in Malaysia. Journal of Advanced Research in Applied Sciences and Engineering Technology, 26 (1). 15 -22. ISSN 24621943, DOI

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E-cigarette has been marketed over years as one of alternative smoking cessation aid offered for consumer worldwide. The addition of flavouring in e-liquid has become a major factor that contributes to the appeal of using e-cigarette among a non-smoker and youngster has raised concerns due to possible risk and hazard outcomes in daily usage is remain unclear to date. In order to fully understand the e-cigarette attributes towards human health and environment; 17 e-liquid products locally sold were bought and analysed by gas chromatography-mass spectrometer (GC-MS) in order to determine the chemical constituent of e-liquid, especially the flavouring additive. A total of 19 out of 41 identified chemical compounds were detected as a new flavouring agent used i n e-liquid products since there was no previous report on this. Many of the flavour chemicals possessed a risk of inhalation toxicity because they were classified as corrosive and/or irritant, with only a few having acute toxicity and the potential to cause cancer. Moreover, several chemical compounds to be concerned such as stimulant as well as opioid types were unexpectedly identified in the e-liquid. Thus, this finding indicate that the chemical constituent of e-liquid contained unknown risk of toxicity and further research is needed to fully understand the possibility of adverse effect in using e-cigarette. © 2022, Penerbit Akademia Baru. All rights reserved.

Item Type: Article
Funders: Research University, Ministry of Health, Universiti Teknologi Malaysia, Malaysia Japan International Institute of Technology, Universiti Teknologi Malaysia
Uncontrolled Keywords: E-cigarette; E-liquid; Flavouring additive; Youngster
Subjects: T Technology > TP Chemical technology
Divisions: Faculty of Engineering > Department of Mechanical Engineering
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Nov 2023 08:16
Last Modified: 30 Nov 2023 08:16

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