A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians

Ng, K.H. and Siar, Chong Huat (1996) A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians. The Journal of Laryngology & Otology, 110 (8). pp. 757-762. ISSN 0022-2151, DOI https://doi.org/10.1017/S0022215100134887.


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Official URL: https://doi.org/10.1017/S0022215100134887


We reviewed the clinicopathological characteristics of 13 cases of calcifying epithelial odontogenic tumour (CEOT) (Pindborg tumour) diagnosed in the Division on Stomatology, Institute for Medical Research, Kuala Lumpur, over a 29-year period. There were eight female and five male patients. These consisted of eight (61.5 per cent) Malays, three (23.1 per cent) Chinese, one (7.7 per cent) Indian and one (7.7 per cent) Melanau. Their ages at presentation ranged from 19-61 years (mean age, 31.8 years). There were 12 central and one peripheral CEOT. Of these, 76.9 per cent of cases were located in the maxilla, the remaining in the mandible. The commonest clinical diagnosis was a dentigerous cyst (66.7 per cent). Enucleation was the main mode of treatment. Histologically, sheets and strands of polyhedral epithelial cells containing eosinophilic, homogeneous globules with Liesegang rings were observed. One case also showed extensive calcification and clear cell differentiation. Immunohistochemistry revealed a variable keratin staining of the CEOT epithelium, confirming its heterogeneity.

Item Type: Article
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Uncontrolled Keywords: Jaw neoplasms odontogenic tumours langerhans cells cementum Jaw neoplasms Odontogenic tumours adult article calcification cell differentiation clinical article clinical feature enucleation eosinophil epithelium cell epithelium tumor female human malaysia male mandible tumor maxilla tumor odontogenic tumor teratoma Humans Immunohistochemistry Keratins Maxillary Neoplasms Middle Aged Odontogenic Cyst, Calcifying Tumor Markers, Biological
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Ms Nursyafiqah Abd Malek
Date Deposited: 10 Jan 2013 00:07
Last Modified: 20 Feb 2020 03:28
URI: http://eprints.um.edu.my/id/eprint/4301

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