Delayed presentation of HIV among older individuals: A growing problem

Justice, Amy C. and Goetz, Matthew B. and Stewart, Cameron N. and Hogan, Brenna C. and Humes, Elizabeth and Luz, Paula M. and Castilho, Jessica L. and Nash, Denis and Brazier, Ellen and Musick, Beverly and Yiannoutsos, Constantin and Malateste, Karen and Jaquet, Antoine and Cornell, Morna and Shamu, Tinei and Rajasuriar, Reena and Jiamsakul, Awachana and Althoff, Keri N. (2022) Delayed presentation of HIV among older individuals: A growing problem. The Lancet HIV, 9 (4). E269-E280. ISSN 2352-3018, DOI

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Late presentation for care is a major impediment to the prevention and effective treatment of HIV infection. Older individuals are at increased risk of late presentation, represent a growing proportion of people with late presentation, and might require interventions tailored to their age group. We provide a summary of the literature published globally between 2016-21 (reporting data from 1984-2018) and quantify the association of age with delayed presentation. Using the most common definitions of late presentation and older age from these earlier studies, we update this work with data from the International Epidemiology Databases to Evaluate AIDS (IeDEA) consortium, focusing on data from 2000-19, encompassing four continents. Finally, we consider how late presentation among older individuals might be more effectively addressed as electronic medical records become widely adopted.

Item Type: Article
Funders: US National Institutes of Health's National Institute of Allergy and Infectious Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Cancer Institute, US National Institute of Mental Health, US National Institute on Drug Abuse, US National Heart, Lung, and Blood Institute, US National Institute on Alcohol Abuse and Alcoholism, US National Institute of Diabetes and Digestive and Kidney Diseases, Fogarty International Center, US National Library of Medicine (AsiaPacific) (Grant No: U01AI069907), Harmonist project (Grant No: R24AI24872), National Library of Medicine (CCASAnet) (Grant No: U01AI069923), National Library of Medicine (Central Africa) (Grant No: U01AI096299), National Library of Medicine (East Africa) (Grant No: U01AI069911), National Library of Medicine (NA-ACCORD) (Grant No: U01AI069918), National Library of Medicine (West Africa) (Grant No: U01AI069919), National Library of Medicine (Southern Africa) (Grant No: U01AI069924)
Uncontrolled Keywords: Risky sexual-behavior; Preexposure prophylaxis; Missed opportunities; Alcohol-consumption; Cost-effectiveness; Infected patients; Condom use; Veterans; Health; Adults
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Medicine Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 18 Oct 2023 05:04
Last Modified: 18 Oct 2023 05:04

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