Trends and challenges in phytotherapy and phytocosmetics for skin aging

Ahmed, Idris Adewale and Mikail, Maryam Abimbola and Zamakshshari, Nor Hisam and Mustafa, Mohd Rais and Mohd Hashim, Najihah and Othman, Rozana (2022) Trends and challenges in phytotherapy and phytocosmetics for skin aging. Saudi Journal of Biological Sciences, 29 (8). ISSN 1319-562X, DOI

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Oxidative stress and inflammation mostly contribute to aging and age-related conditions including skin aging. The potential of natural products in the form of naturally-derived cosmetics, cosmeceuticals, and nutricosmetics have, however, not been fully harnessed. This review, thus, critically analyzes the potential roles of natural products in inflammation-related skin aging diseases due to the increasing consumers' concerns and demands for efficacious, safe, natural, sustainable, and religiously permitted alternatives to synthetic products. The information and data were collated from various resources and literature databases such as PubMed, Science Direct, Wiley, Springer, Taylor and Francis, Scopus, Inflibnet, Google, and Google Scholar using relevant keywords and Medical Subject Headings (MeSH). The role of green extraction solvents as promising alternatives is also elucidated. The potential enhancements of the bioavailability, stability, solubility and controlled release profile of the bioactives using different delivery systems are also presented. The current potential global market value, motivators, drivers, trends, challenges, halal, and other regulatory certifications for cosmeceuticals and nutricosmetics are equally discussed. The adoption of the suggested extractions and delivery systems would enhance the stability, bioavailability, and target delivery of the bioactives. (C) 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.

Item Type: Article
Funders: Universiti Malaya, IIRG002-2019
Uncontrolled Keywords: Aging; Cosmetics; Certifications; Eutectic solvents; Hormesis; Inflammation
Subjects: Q Science > QH Natural history
Q Science > QH Natural history > QH301 Biology
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Centre for Natural Products Research and Drug Discovery (CENAR)
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Nov 2023 08:22
Last Modified: 22 Nov 2023 08:22

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