A global view of adherence to colonoscopy follow-up in cascade screening of colorectal cancer

Yang, Yihui and Huang, Junjie and Wu, Weimiao and Luu, Hung N. and Foong, Ming Moy and Tan, Songsong and Fu, Jiongxing and Ying, Tao and Withers, Mellissa and Hung, Dang The and Mao, Dandan and Chen, Sikun and Wong, Martin C. S. and Xu, Wanghong (2022) A global view of adherence to colonoscopy follow-up in cascade screening of colorectal cancer. European Journal of Cancer Care, 31 (5). ISSN 0961-5423, DOI https://doi.org/10.1111/ecc.13577.

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To overview the colonoscopy adherence in cascade screening of colorectal cancer (CRC) and evaluate potential influence of the initial tests based on an ecological evaluation. Methods The performance of the initial screening tests and adherence to subsequent colonoscopy were extracted from relevant studies published up to 16 October 2020. The age-standardised incidence (ASRi) of CRC in populations in the year of screening was derived from the Cancer Statistics. Results One hundred sixty-six observational studies and 60 experimental studies were identified. Most studies applied cascade screening with faecal occult blood tests (FOBTs) as an initial test. The adherence to colonoscopy varied greatly across populations by continents, gross national income and type of initial tests, with a median (interquartile range) of 79.8% (63.1%-87.8%) in observational studies and 82.1% (66.7%-90.4%) in randomised trials. The adherence was positively correlated with the ASRi of CRC (r = 0.145, p = 0.023) and positive predictive value (PPV) of the initial tests (r = 0.206, p = 0.002) in observational studies and correlated with ASRi of CRC (r = 0.309, p = 0.002) and sensitivity of the initial tests (r = -0.704, p = 0.003) in experimental studies. Conclusions Adherence to colonoscopy varies greatly across populations and is related with performance of the initial tests, indicating the importance to select appropriate initial tests.

Item Type: Article
Funders: Health Commission of Pudong New Area of Shanghai [PW2019A5], Local High Level University Construction Project of Shanghai
Uncontrolled Keywords: Adherence to colonoscopy; Colorectal cancer screening; Ecological study; Initial screening tests
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 25 Sep 2023 03:54
Last Modified: 25 Sep 2023 03:54
URI: http://eprints.um.edu.my/id/eprint/41473

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