Blood pressure variability and cognitive function: A scoping review

Asmuje, Nur Fazidah and Mat, Sumaiyah and Myint, Phyo Kyaw and Tan, Maw Pin (2022) Blood pressure variability and cognitive function: A scoping review. Current Hypertension Reports, 24 (10). pp. 375-383. ISSN 1522-6417, DOI

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To conduct a scoping review of articles which have evaluated BPV and cognitive function. Articles with keywords, titles or abstracts containing the terms `cognitive' OR `cognition' OR `dementia' AND `blood pressure variability' were identified from CINAHL, Medline, PMC and Web of Science. Recent Findings Methods of acquisition and analysis of BPV and cognitive measurements and their relationship were extracted from selected articles. Of 656 studies identified, 53 articles were selected. Twenty-five evaluated long-term (LTBPV), nine mid-term (MTBPV), 12 short-term (STBPV) and nine very short-term BPV (VSTBPV) with conflicting findings on the relationship between BPV and cognition. Variations existed in devices, period and procedure for acquisition. The studies also utilized a wide range of methods of BPV calculation. Thirteen cognitive assessment tools were used to measure global cognition or domain functions which were influenced by the population of interest. The interpretation of available studies was hence limited by heterogeneity. There is an urgent need for standardization of BPV assessments to streamline research on BPV and cognition. Future studies should also establish whether BPV could be a potential modifiable risk factor for cognitive decline, as well as a marker for treatment response.

Item Type: Article
Funders: Ministry of Higher Education Long Term Research Grant Scheme [LRGS/1/2019/UM/01/1]
Uncontrolled Keywords: Aged; Cognition; Dementia; Blood pressure; Blood pressure variability
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 15 Sep 2023 01:57
Last Modified: 15 Sep 2023 01:57

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