Molecular evidence of rat bocavirus among rodents in Peninsular Malaysia

Mohd-Azami, Siti Nurul Izzah and Loong, Shih Keng and Khoo, Jing Jing and Sahimin, Norhidayu and Lim, Fang Shiang and Husin, Nurul Aini and Mahfodz, Nur Hidayana and Mohd-Taib, Farah Shafawati and Ishak, Siti Nabilah and Makepeace, Benjamin L. and Abubakar, Sazaly (2022) Molecular evidence of rat bocavirus among rodents in Peninsular Malaysia. Journal of Veterinary Medical Science, 84 (7). pp. 938-941. ISSN 0916-7250, DOI

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Rat bocavirus (RBoV) and rodent bocavirus (RoBoV) have previously been detected in Rattus norvegicus; however, these viruses have not been reported in rodent populations in Malaysia. We investigated the presence of RBoV and RoBoV in archived rodent specimens. DNA barcoding of the rodent cytochrome c oxidase gene identified five different species: Rattus tanezumi R3 mitotype, Rattus tiomanicus, Rattus exulans, Rattus argentiventer, and Rattus tanezumi sensu stricto. Three spleens were positive for RBoV (1.84%; 3/163), but no RoBoV was detected. Phylogenetic analyzes of the partial non-structural protein 1 gene grouped Malaysian RBoV strains with RBoV strains from China. Further studies among rats from different geographical locations are warranted for this relatively new virus.

Item Type: Article
Funders: Ministry of Education, Malaysia [MO002-2019], Newton-Ungku Omar Fund partnership [332192305], UK Department of Business, Energy, and Industrial Strategy (BEIS), Malaysian Industry Government Group for High Technology (MIGHT)
Uncontrolled Keywords: Infectious disease; Malaysia; Rat bocavirus; Rattus sp; Rodent
Subjects: R Medicine
Divisions: Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Sep 2023 08:11
Last Modified: 14 Sep 2023 08:11

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