Synthesis, biomedical applications, and toxicity of CuO nanoparticles

Naz, Sania and Gul, Ayesha and Zia, Muhammad and Javed, Rabia (2023) Synthesis, biomedical applications, and toxicity of CuO nanoparticles. Applied Microbiology and Biotechnology, 107 (4). pp. 1039-1061. ISSN 0175-7598, DOI

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Versatile nature of copper oxide nanoparticles (CuO NPs) has made them an imperative nanomaterial being employed in nanomedicine. Various physical, chemical, and biological methodologies are in use for the preparation of CuO NPs. The physicochemical and biological properties of CuO NPs are primarily affected by their method of fabrication; therefore, selectivity of a synthetic technique is immensely important that makes these NPs appropriate for a specific biomedical application. The deliberate use of CuO NPs in biomedicine questions their biocompatible nature. For this reason, the present review has been designed to focus on the approaches employed for the synthesis of CuO NPs; their biomedical applications highlighting antimicrobial, anticancer, and antioxidant studies; and most importantly, the in vitro and in vivo toxicity associated with these NPs. This comprehensive overview of CuO NPs is unique and novel as it emphasizes on biomedical applications of CuO NPs along with its toxicological assessments which would be useful in providing core knowledge to researchers working in these domains for planning and conducting futuristic studies.

Item Type: Article
Funders: None
Uncontrolled Keywords: CuO NPs; Toxicity; Green synthesis; Biocompatibility; ROS; Biomedicine
Subjects: Q Science > QR Microbiology
R Medicine > R Medicine (General)
Divisions: Nanotechnology & Catalysis Research Centre
Depositing User: Ms Zaharah Ramly
Date Deposited: 30 Nov 2023 08:23
Last Modified: 30 Nov 2023 08:23

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