Chronic kidney disease-associated pruritus and quality of life in Malaysian patients undergoing hemodialysis

Rehman, Inayat U. and Lai, Pauline Siew Mei and Lim, Soo Kun and Lee, Learn H. and Chan, Kok Gan and Khan, Tahir M. (2020) Chronic kidney disease-associated pruritus and quality of life in Malaysian patients undergoing hemodialysis. Therapeutic Apheresis and Dialysis, 24 (1). pp. 17-25. ISSN 1744-9979, DOI

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CKD-associated pruritus is one of the common symptoms in patients undergoing dialysis, thus contributing to the diminished and compromised quality of life. This study aimed to explore the association between the CKD-associated pruritus on quality of life of patients undergoing hemodialysis in Malaysia. A cross-sectional multicenter study, carried out from February to September 2017 at tertiary care settings in Kuala Lumpur, Malaysia. Patients aged 18 years and above, undergoing hemodialysis, understanding Malay language and willing to participate were included. The CKD-associated pruritus was assessed by using Malay 5D-itch scale and Malay FANLTC questionaiare. To determine the factors associated with pruritus and quality of life, multivariate logistic regression analysis was used having P value < 0.05 as statistically significant. Among n = 334 recruited patients with a response rate of 100%, 59.6% were males and total of 61.3% were having CKD-associated pruritus. The results showed a statistically significant weak negative correlation between CKD-associated pruritus and quality of life. Multivariate linear regression revealed none of these factors were found to be associated with pruritus; however, CKD-associated prurtius was found to be associated with quality of life score. CKD-associated pruritus is have a negative impact on the patient's quality of life including physical, social, mental/emotional, and functional well-being. Despite the high prevalence and negative impact of CKD-associated pruritus on quality of life, it is disregarded by most health care professionals. It is thus pertinent to monitor the potential risk factors and consider providing timely treatment implications for CKD-associated pruritus in hemodialysis patients, in order to improve their quality of life.

Item Type: Article
Funders: None
Uncontrolled Keywords: 5D itch scale; Chronic kidney disease-associated pruritus; Hemodialysis; Malaysia; Quality of life
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Medicine Department
Faculty of Science > Institute of Biological Sciences
Depositing User: Ms Zaharah Ramly
Date Deposited: 25 Oct 2023 09:04
Last Modified: 25 Oct 2023 09:04

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