A comparative study of sevoflurane sedation with nitrous oxide sedation for dental surgery

Wang, C.Y. and Chiu, C.L. and Har, K.O. and Chan, C. and Rahman, Z.A.A. (2002) A comparative study of sevoflurane sedation with nitrous oxide sedation for dental surgery. International Journal of Oral and Maxillofacial Surgery, 31 (5). pp. 506-510. ISSN 0901-5027, DOI https://doi.org/10.1054/ijom.2002.0293.

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This study compares the use of inhalation sedation using sevoflurane (group S) with inhalation sedation using nitrous oxide (group N) in patients undergoing bilateral extraction of third molar teeth under local anaesthesia. The study was designed as a cross-over study. Seventeen ASA I, day surgery patients were studied. Patients were randomly allocated to receive either 8 I/min 50 nitrous oxide in oxygen (group N) or same flow of 1 sevoflurane (group S) for the first procedure. Each patient then had the alternate method of sedation for the second procedure. There were no significant differences between the methods in patient co-operation and surgeon's satisfaction with sedation. Psychomotor tests were comparable in both groups. The patients were significantly more sedated in the group S compared to group N (P=0.004). Significantly more patients complained of an unpleasant odour group S (P<0.01) but none withdrew from the study for this reason. No adverse cardiorespiratory effects resulted from sevoflurane or nitrous oxide sedation. Both methods gave good amnesia during the procedure. There was high acceptance of both methods and the patients rated the technique as equally satisfactory. We conclude that inhalation sedation with sevoflurane is a suitable alternative method to nitrous oxide sedation.

Item Type: Article
Additional Information: ISI Document Delivery No.: 604YL Times Cited: 5 Cited Reference Count: 15 Cited References: AMESS JAL, 1978, LANCET, V2, P339 COLEMAN AJ, 1984, PRACTICAL ANAESTHESI, P167 CRAIG J, 1982, BRIT J ANAESTH, V54, P447, DOI 10.1093/bja/54.4.447 EGER EI, 1981, ISOFLURANE FORANE CO HARAGUCHI N, 1995, J ORAL MAXIL SURG, V53, P24, DOI 10.1016/0278-2391(95)90493-X KATOH T, 1992, BRIT J ANAESTH, V69, P259, DOI 10.1093/bja/69.3.259 LANGA RA, 1976, RELATIVE ANALGESIA D MCLEOD DD, 1985, ANAESTHESIA, V40, P424 MELAMED SF, 1985, GUIDE PATIENT MANAGE OSBORNE GA, 1994, ANAESTHESIA, V49, P287, DOI 10.1111/j.1365-2044.1994.tb14175.x SWEENEY B, 1985, BRIT MED J, V291, P567 WALIN RF, 1975, ANESTH ANALG, V54, P758 Wang CY, 2000, BRIT J ANAESTH, V85, P668 WINTER PM, ANN M AM SOC AN 1972, P103 YURINO M, 1995, ANAESTHESIA, V50, P308, DOI 10.1111/j.1365-2044.1995.tb04605.x Wang, CY Chiu, CL Har, KO Chan, C Rahman, ZAA Churchill livingstone Edinburgh
Uncontrolled Keywords: anaesthetics inhalation sevoflurane anaesthetics inhalation nitrous oxide sedation inhalation surgery oral inhalation sedation anesthesia recovery
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of Oral & Maxillofacial Surgery
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 24 Sep 2012 01:49
Last Modified: 24 Sep 2012 01:49
URI: http://eprints.um.edu.my/id/eprint/3686

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