Associations of an empirical dietary pattern with cardiometabolic risk factors in Malaysian adolescents

Emi, Nor Aishah and Gan, Wan Ying and Shariff, Zalilah Mohd and Zaini, Azriyanti Anuar and Shamsuddin, Nurainul Hana and Appukutty, Mahenderan and Appannah, Geeta (2020) Associations of an empirical dietary pattern with cardiometabolic risk factors in Malaysian adolescents. Nutrition and Metabolism, 17 (1). ISSN 17437075,

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Background: This study aimed to identify a dietary pattern (DP) characterised mainly by high intakes of free sugar and other nutrients hypothesised to be associated with obesity such as dietary energy density (DED), percentage of energy from total fat and fibre density in adolescents from three southern states of Peninsular Malaysia, and its associations with cardiometabolic risk factors. Methods: This is a cross-sectional study among 335 adolescents who provided both dietary information assessed using a validated food frequency questionnaire (FFQ) and biochemical parameters including lipid profile, blood glucose, serum insulin and homeostatic model assessment-insulin resistance (HOMA-IR). Anthropometric measurements included weight (kg), height (cm) and waist circumference (cm), while body mass index (BMI) in kg/m(2) was estimated, respectively. Reduced rank regression (RRR) identified a DP with percentage of energy from sugar and total fat, DED and fibre density intake as response variables. Results: The identified `high sugar, high fibre, high DED and low fat' DP was characterised by high intakes of sugar-sweetened beverages, fruits, sweets and low intakes of meat and cereal. Adolescents in the highest tertile of the identified DP had about 3.0 (OR = 2.7; 95%CI: 1.3, 5.6) and 2.0 (OR = 1.9; 95%CI: 1.0, 3.5) times higher odds of having dyslipideamia or elevated total cholesterol and LDL-cholesterol level, respectively compared to adolescents in the lowest tertile DP after adjusting for sex, school location, maternal education, physical activity, dietary misreporting and BMI z-score. This DP was not significantly associated with overweight and obesity. Conclusions: Higher adherence to a DP characterised mainly by free sugars and DED was associated with greater odds of having dyslipideamia, elevated total cholesterol and LDL-cholesterol levels in Malaysian adolescents.

Item Type: Article
Uncontrolled Keywords: Dietary patterns; Dyslipidemia; Cardiometabolic risk factors; Childhood obesity; Malaysian adolescent
Subjects: R Medicine > R Medicine (General)
R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine
Faculty of Medicine > Paediatrics Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 01 Dec 2023 03:02
Last Modified: 01 Dec 2023 03:02

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