Recurrent ischemic and hemorrhagic stroke in Cameroon: A case-control study

Kamgang, Jaures and Tetinou, Francklin and Zolo, Yvan and Tan, Chee Yang and Wambo, Christian and Fongang, Emerancienne J. Nguifo and Kanmounye, Ulrick Sidney (2021) Recurrent ischemic and hemorrhagic stroke in Cameroon: A case-control study. Neurology Research International, 2021. ISSN 2090-1852, DOI

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Stroke recurrence accounts for a great percentage of catastrophic complications, yet no comprehensive study has analyzed the factors associated with stroke recurrence in Cameroon. We carried out this case-control study to better understand the factors associated with the stroke recurrence in Cameroon. Methods. We collected sociodemographic, clinical, neuroimaging, laboratory, and therapeutic data of eligible patients who consulted the neurology and cardiology department of the Yaounde Central Hospital in Cameroon. We included all patients at least five years removed from their first stroke event who consulted the authors' institution as of January 15, 2019. Wilcoxon signed-rank and Fisher's exact tests were used. Also, a Cox regression model was used to identify confounders.Results. We recruited 100 patients; seven out of ten patients had hypertension, while six out of 10 had a sedentary lifestyle. Half of the patients consumed alcohol regularly, while one patient out of five had diabetes. Most patients presented with their first stroke event, and a quarter had a stroke recurrence. Stroke recurrence was associated with right handedness (OR = 0.23, 95% CI = 0.16-0.33), congestive heart failure (OR = 3.45, 95% CI = 1.16-10.28), gout (OR = 4.34, 95% CI = 1.09-18.09), dysarthria (OR = 4.34, 95% CI = 1.30-14.54), and facial palsy (OR = 3.96, 95% CII = 1.49 - 10.51), as well as modifiable factors such as elevated abdominal circumference (P < 0.01), systolic blood pressure (P < 0.01), blood glucose level (PI <I 0.01), LDL cholesterol (P < 0.01), and triglyceride levels (P < 0.01). The mulitvariable regression model only identified laterality (B = -1.48, P = 0.04) as a statistically significant explanatory varibale for stroke recurrence. Conclusion. We mapped the landscape of recurrent strokes in Cameroon. There is a need to evaluate the causes of suboptimal drug adherence rates and both the role and adherence to nonpharmacologic interventions.

Item Type: Article
Uncontrolled Keywords: Risk-factors;Predictors;Mortality;Outcomes;Events;Rates
Subjects: R Medicine
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Depositing User: Ms Zaharah Ramly
Date Deposited: 08 Sep 2022 01:09
Last Modified: 08 Sep 2022 01:09

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