Coenzyme, cofactor and prosthetic group : ambiguous biochemical jargon

Hashim, Onn Haji and Adnan, N.A. (1994) Coenzyme, cofactor and prosthetic group : ambiguous biochemical jargon. Biochemical Education, 22 (2). pp. 93-94. ISSN 1879-1468, DOI

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For enzymes which require non-protein components to be functionally active, it is generally accepted that the term holoenzyme refers to the complete catalytic entity which consists of a protein part known as the apoenzyme and a non-protein constituent. The terms used for the functionally required non-protein constituents however, are ambiguous and differ from one commonly used biochemistry textbook to another. In certain textbooks, any associative non-protein factor required for the enzymatic function is termed coenzyme. The coenzyme may eitherbe a prosthetic group — the tightly bound coenzyme, or a cofactor — the loosely bound small organic or inorganic molecule.

Item Type: Article
Additional Information: Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Molecular Medicine
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 11 Jul 2012 01:48
Last Modified: 24 Oct 2019 08:15

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