Factors affecting COVID-19 vaccine acceptance: An international survey among low-and middle-income countries

Bono, Suzanna Awang and Faria de Moura Villela, Edlaine and Siau, Ching Sin and Chen, Won Sun and Pengpid, Supa and Hasan, M. Tasdik and Sessou, Philippe and Ditekemena, John D. and Amodan, Bob Omoda and Hosseinipour, Mina C. and Dolo, Housseini and Siewe Fodjo, Joseph Nelson and Low, Wah Yun and Colebunders, Robert (2021) Factors affecting COVID-19 vaccine acceptance: An international survey among low-and middle-income countries. Vaccines, 9 (5). ISSN 2076-393X, DOI https://doi.org/10.3390/vaccines9050515.

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Vaccination is fast becoming a key intervention against the ongoing COVID-19 pandemic. We conducted cross-sectional online surveys to investigate COVID-19 vaccine acceptance across nine Low- and Middle-Income Countries (LMICs; N = 10,183), assuming vaccine effectiveness at 90% and 95%. The prevalence of vaccine acceptance increased from 76.4% (90% effectiveness) to 88.8% (95% effectiveness). Considering a 90% effective vaccine, Malaysia, Thailand, Bangladesh, and five African countries (Democratic Republic of Congo, Benin, Uganda, Malawi, and Mali) had lower acceptance odds compared to Brazil. Individuals who perceived taking the vaccine as important to protect themselves had the highest acceptance odds (aOR 2.49) at 95% effectiveness.Vaccine acceptance was also positively associated with COVID-19 knowledge, worry/fear regarding COVID-19, higher income, younger age, and testing negative for COVID-19. However, chronic disease and female gender reduced the odds for vaccine acceptance. The main reasons underpinning vaccine refusal were fear of side effects (41.2%) and lack of confidence in vaccine effectiveness (15.1%). Further research is needed to identify country-specific reasons for vaccine hesitancy in order to develop mitigation strategies that would ensure high and equitable vaccination coverage across LMICs.

Item Type: Article
Funders: VLIRUOS (Flemish Interuniversity Council for University Development Cooperation)
Uncontrolled Keywords: COVID-19; Vaccine acceptance; LMICs; Healthcare worker; Psychological distress; Brazil; Malaysia; Thailand; Bangladesh; Africa
Subjects: Q Science > QR Microbiology > QR180 Immunology
Divisions: Faculty of Medicine
Depositing User: Ms Zaharah Ramly
Date Deposited: 31 May 2022 07:39
Last Modified: 31 May 2022 07:40
URI: http://eprints.um.edu.my/id/eprint/34489

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