Cellulose supported magnetic nanohybrids: Synthesis, physicomagnetic properties and biomedical applications-a review

Haniffa, Mohamed Abdul Cader Mohamed and Munawar, Khadija and Chee, Ching Yern and Pramanik, Sumit and Halilu, Ahmed and Illias, Hazlee Azil and Rizwan, Muhammad and Senthilnithy, Rajendram and Mahanama, Kariyawasam Ranaweerage Ranjith and Tripathy, Ashis and Azman, Mohd Fahmi (2021) Cellulose supported magnetic nanohybrids: Synthesis, physicomagnetic properties and biomedical applications-a review. Carbohydrate Polymers, 267. ISSN 0144-8617, DOI https://doi.org/10.1016/j.carbpol.2021.118136.

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Cellulose and its forms are widely used in biomedical applications due to their biocompatibility, biodegradability and lack of cytotoxicity. It provides ample opportunities for the functionalization of supported magnetic nanohybrids (CSMNs). Because of the abundance of surface hydroxyl groups, they are surface tunable in either homogeneous or heterogeneous solvents and thus act as a substrate or template for the CSMNs' development. The present review emphasizes on the synthesis of various CSMNs, their physicomagnetic properties, and potential applications such as stimuli-responsive drug delivery systems, MRI, enzyme encapsulation, nucleic acid extraction, wound healing and tissue engineering. The impact of CSMNs on cytotoxicity, magnetic hyperthermia, and folate-conjugates is highlighted in particular, based on their structures, cell viability, and stability. Finally, the review also discussed the challenges and prospects of CSMNs' development. This review is expected to provide CSMNs' development roadmap in the context of 21st-century demands for biomedical therapeutics.

Item Type: Article
Funders: Faculty of Engineering, University of Malaya[H-16001-D00048], Faculty of Engineering, University of Malaya[GPF077A-2018], Faculty of Engineering, University of Malaya[IIRG001-2020IISS]
Uncontrolled Keywords: Magneto-responsive cellulose;Cancer therapy;Drug delivery; MRI;Enzyme immobilization;Folate-conjugate
Subjects: Q Science > QC Physics
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions: Faculty of Engineering
Depositing User: Ms Zaharah Ramly
Date Deposited: 15 Jun 2022 02:50
Last Modified: 15 Jun 2022 02:50
URI: http://eprints.um.edu.my/id/eprint/34428

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