Extraction and application of keratin from natural resources: a review

Chilakamarry, Chaitanya Reddy and Mahmood, Syed and Saffe, Siti Nadiah Binti Mohd and Bin Arifin, Mohd Azmir and Gupta, Arun and Sikkandar, Mohamed Yacin and Begum, S. Sabarunisha and Narasaiah, Boya (2021) Extraction and application of keratin from natural resources: a review. 3 Biotech, 11 (5). ISSN 2190-572X, DOI https://doi.org/10.1007/s13205-021-02734-7.

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Over recent years, keratin has gained great popularity due to its exceptional biocompatible and biodegradable nature. It has shown promising results in various industries like poultry, textile, agriculture, cosmetics, and pharmaceutical. Keratin is a multipurpose biopolymer that has been used in the production of fibrous composites, and with necessary modifications, it can be developed into gels, films, nanoparticles, and microparticles. Its stability against enzymatic degradation and unique biocompatibility has found their way into biomedical applications and regenerative medicine. This review discusses the structure of keratin, its classification and its properties. It also covers various methods by which keratin is extracted like chemical hydrolysis, enzymatic and microbial treatment, dissolution in ionic liquids, microwave irradiation, steam explosion technique, and thermal hydrolysis or superheated process. Special emphasis is placed on its utilisation in the form of hydrogels, films, fibres, sponges, and scaffolds in various biotechnological and industrial sectors. The present review can be noteworthy for the researchers working on natural protein and related usage.

Item Type: Article
Funders: Universiti Malaysia Pahang (UMP) [RDU1903137], Ministry of Education Malaysia (MOE) under the Fundamental Research Grant Scheme [FRGS/1/2019/STG05/UMP/02/9], IPS
Uncontrolled Keywords: Keratin; Sheep wool; Feathers; Proteins; Amino acids
Subjects: Q Science > QR Microbiology
T Technology > TP Chemical technology
Divisions: Faculty of Pharmacy > Department of Pharmaceutical Technology
Depositing User: Ms Zaharah Ramly
Date Deposited: 01 Jul 2022 07:10
Last Modified: 01 Jul 2022 07:10
URI: http://eprints.um.edu.my/id/eprint/34025

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