Contrast sensitivity is associated with frailty

Amir, Nurul Najieha and Kamaruzzaman, Shahrul Bahyah and Effendi-Tenang, Irina and Jamaluddin, Marium and Tan, Maw Pin and Ramli, Norlina Mohd and Khaliddin, Nurliza and Zahari, Mimiwati (2021) Contrast sensitivity is associated with frailty. European Geriatric Medicine, 12 (2). pp. 313-319. ISSN 1878-7649, DOI

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Key summary pointsAim To determine the association between visual acuity and contrast sensitivity with frailty measures Findings Older adults with poor contrast sensitivity are significantly more likely to be frail (OR: 5.34, p = 0.004). No association was identified between visual acuity and frailty (p = 0.241). Message Poor contrast sensitivity is significantly associated with frailty. Purpose Using data from the Malaysian Elders Longitudinal Research (MELoR), this study investigated the association between visual function (visual acuity and contrast sensitivity) and frailty in a group of urban-dwelling older adults. Methods This was a cross-sectional study. 1332 participants aged >= 55 years were selected by random sampling from the parliamentary electoral register. Only 1274 participants completed the frailty assessment and 1278 participants completed the contrast sensitivity assessment. Impaired vision was defined as a Snellen visual acuity of worse than 6/12 in the better eye. Poor contrast sensitivity was defined as a score on the Pelli Robson chart of lower than 1.65. Frailty was defined with the Fried's phenotype criteria. Inter-group comparisons were determined with the independent T-test for continuous variables and the Pearson's Chi-squared test for categorical variables. The odds ratio (OR) with 95% confidence interval (CI) was used to evaluate the cross-sectional association between frailty and visual function. Results The mean age of participants was 68.8 +/- 7.5 years, of which 58.1% (774) were women. Impaired vision and poor contrast sensitivity were present in 187 (14%) and 271 (21.2%) subjects respectively. 73 (5.8%) individuals were classified as frail, 1161 (91.0.%) pre-frail, and 40 (2.8%) non-frail. There was no significant difference in frailty phenotypes between those with good and impaired vision (p = 0.241). Fried's component of handgrip strength, gait speed and exhaustion were significantly better in those with good visual function (p < 0.05). Participants with poor contrast sensitivity were significantly more likely to be frail (OR: 5.34, p = 0.004). Conclusion Poor contrast sensitivity was significantly associated with frailty. This highlights the importance of incorporating assessment of contrast sensitivity in those at risk of frailty.

Item Type: Article
Funders: Ministry of Higher Education High Impact Research Grant [UM.C/625/1/HIR/MOHE/ASH/02], Ministry of Higher Education Long Term Research Grant Scheme [LRGS/1/2019/UM//1/1]
Uncontrolled Keywords: Aging; Frailty; MELoR; Poor contrast sensitivity; Vision impairment
Subjects: H Social Sciences > HQ The family. Marriage. Woman
R Medicine > RC Internal medicine
R Medicine > RT Nursing
Divisions: Faculty of Medicine > Medicine Department
Faculty of Medicine > Department of Ophthalmology
Depositing User: Ms Zaharah Ramly
Date Deposited: 01 Aug 2022 01:44
Last Modified: 01 Aug 2022 01:44

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