Upper limb infections: A comparison between diabetic and non-diabetic patients

Lim, Shan Hua and Ahmad, Tunku Sara Tunku and Devarajooh, Cassidy and Gunasagaran, Jayaletchumi (2022) Upper limb infections: A comparison between diabetic and non-diabetic patients. Journal of Orthopaedic Surgery, 30 (1). ISSN 2309-4990, DOI https://doi.org/10.1177/23094990221075376.

Full text not available from this repository.


Upper limb infections are common among patients with diabetes mellitus and their sequelae can be debilitating. They tend to present with severe infections but minimal symptoms probably due to neuropathy and vasculopathy among diabetics. The study aims to compare the demographic characteristics, clinical presentations and outcomes of upper limb infections between diabetic and non-diabetic patients. Methods All patients with upper limb infections who were admitted in a tertiary hospital from June 2017 to December 2020 were included in this study. Demographic data, clinical presentations, investigations and outcomes were obtained retrospectively from electronic medical record. There were 117 patients with diabetes mellitus and 127 with no diabetes mellitus. Comparisons were made between these two groups, and statistical analysis was done with SPSS. Results There were 244 patients included; 117 were diabetic and 127 were non-diabetic. Diabetic patients were more likely to present with emergent scenarios, especially necrotizing fasciitis and infective tenosynovitis (p < .05) with higher erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) readings (p < .05). Their microbiological cultures were less likely to be negative (p < .05). Diabetic patients also had poorer clinical outcomes with higher risk of amputation, re-operation and longer duration of hospital stay (p < .05). Conclusion Upper limb infections among diabetic patients should be treated aggressively. Early diagnosis and surgical intervention might decrease the morbidity and mortality in this group. Prevention of infections should be emphasized.

Item Type: Article
Uncontrolled Keywords: Upper limb infections;Diabetes;Amputation;Re-operation; Duration of hospital stay
Subjects: R Medicine
R Medicine > RD Surgery
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 03 Aug 2022 08:03
Last Modified: 03 Aug 2022 08:03
URI: http://eprints.um.edu.my/id/eprint/33565

Actions (login required)

View Item View Item