Beverage consumption and ulcerative colitis: A case-control study from Saudi Arabia

Almofarreh, Anas and Sheerah, Haytham A. and Arafa, Ahmed and Ahamed, Shaik Shaffi and Alzeer, Osama and Al-Hunaishi, Weiam and Mhimed, Mohamed Ma and Al-Hazmi, Ali and Lim, Sin How (2022) Beverage consumption and ulcerative colitis: A case-control study from Saudi Arabia. International Journal of Environmental Research and Public Health, 19 (4). ISSN 1660-4601, DOI

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Background: The association between beverage intake and ulcerative colitis (UC) is not well-established, with no available data from Arab countries. Herein, we investigated the potential association of consuming coffee, tea, and carbonated soft drinks with UC among a population from Saudi Arabia. Methods: This hospital-based case-control study used data of 171 newly diagnosed UC patients and 400 patients with other gastrointestinal conditions who served as controls. All UC cases were ascertained by endoscopy, while beverage intake was assessed by a questionnaire that was completed before diagnosis. We computed odds ratios (ORs) and 95% confidence intervals (95% CIs) of UC and UC extension for frequent versus infrequent intakes of coffee, tea, and carbonated soft drinks using logistic regression. Results: Overall, 23.4% of UC patients had pancolitis, 21.1% extensive, 51.4% left-sided, and 4.1% proctitis. UC patients had a similar sex distribution to the controls but were older and had a lower BMI. After adjustment for age, sex, body mass index, and smoking history, frequent intakes of coffee and tea were associated with lower odds of UC: 0.62 (0.42, 0.91) and 0.53 (0.35, 0.79), respectively. On the other hand, frequent intakes of carbonated soft drinks were associated with increased odds of UC: 9.82 (6.12, 15.76). The frequency of beverage consumption was not associated with UC extension. Conclusion: UC was negatively associated with frequent coffee and tea consumption but positively associated with frequent carbonated soft drink intake in Saudi people. More population-based prospective cohort studies are needed to confirm our findings.

Item Type: Article
Funders: None
Uncontrolled Keywords: Ulcerative colitis; Tea; Coffee; Carbonated soft drinks; Case-control study; Saudi Arabia
Subjects: G Geography. Anthropology. Recreation > GE Environmental Sciences
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 08 Aug 2022 07:18
Last Modified: 08 Aug 2022 07:18

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