Small open reading frames in plant research: From prediction to functional characterization

Ong, Sheue Ni and Tan, Boon Chin and Al-Idrus, Aisyafaznim and Teo, Chee How (2022) Small open reading frames in plant research: From prediction to functional characterization. 3 Biotech, 12 (3). ISSN 2190-572X, DOI

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Gene prediction is a laborious and time-consuming task. The advancement of sequencing technologies and bioinformatics tools, coupled with accelerated rate of ribosome profiling and mass spectrometry development, have made identification of small open reading frames (sORFs) (< 100 codons) in various plant genomes possible. The past 50 years have seen sORFs being isolated from many organisms. However, to date, a comprehensive sORF annotation pipeline is as yet unavailable, hence, addressed in our review. Here, we also provide current information on classification and functions of plant sORFs and their potential applications in crop improvement programs.

Item Type: Article
Funders: Ministry of Higher Education, Malaysia, under the Fundamental Research Grant Scheme (FRGS) [Grant No: FRGS/1/2019/STG05/UM/02/3]
Uncontrolled Keywords: Small open reading frame; Small peptide; sORFs; SEP; Hormone-like peptides
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Science > Institute of Biological Sciences
Deputy Vice Chancellor (Research & Innovation) Office > Centre for Research in Biotechnology for Agriculture
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 08 Aug 2022 07:10
Last Modified: 08 Aug 2022 07:10

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