Coffee and tea intake and risk of Breast Cancer

Pathy, N.B. and Peeters, P. and van Gils, C. and Beulens, J.W.J. and van der Graaf, Y. and Bueno-de-Mesquita, B. and Bulgiba, A. and Uiterwaal, C.S.P.M. (2010) Coffee and tea intake and risk of Breast Cancer. Breast Cancer Research and Treatment, 121 (2). pp. 461-467. ISSN 0167-6806, DOI

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Known risk factors account for about 10-15 of breast cancer incidence suggesting that lifestyle exposures are crucial in its etiology. Previous epidemiological studies on the association between coffee and tea consumption and breast cancer risk have been inconsistent. We investigated the association of coffee and tea consumption with the risk of breast cancer among women in EPIC-NL cohort, a population-based prospective cohort in Netherlands with 27,323 participants. Exposure was measured by a validated food frequency questionnaire, and the outcome was verified by direct linkage with the Netherlands Cancer Registry. A total of 681 invasive primary breast cancers were diagnosed in 9.6 years of follow-up. Coffee intake increased the risk of breast cancer by more than twofold as compared to non-consumers (HR; 2.25, 95 CI; 1.30-3.90). This association did not hold after multivariate adjustment which resulted in a HR of 1.17, 95 CI; 0.65-2.12. After adjustment to breast cancer risk factors and lifestyle, no association was observed between intake of coffee or tea and risk of breast cancer across all categories of intake. These results were also not altered by body mass index (BMI). Coffee and tea consumption does not seem to be related to the risk of breast cancer in women.

Item Type: Article
Additional Information: Pathy, Nirmala Bhoo Peeters, Petra van Gils, Carla Beulens, Joline W. J. van der Graaf, Yolanda Bueno-de-Mesquita, Bas Bulgiba, Awang Uiterwaal, Cuno S. P. M. --------> Suggested Citation : Pathy NB, Peeters P, van Gils C, Beulens JWJ, van der Graaf Y, Bueno-de-Mesquita B, et al. Coffee and tea intake and risk of breast cancer. Breast Cancer Research and Treatment. 2010 Jun;121(2):461-7.
Uncontrolled Keywords: Coffee, Tea, Breast cancer
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Awang Bulgiba Awang Mahmud
Date Deposited: 09 May 2012 06:39
Last Modified: 30 Dec 2014 02:50

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