Borosilicate glass Co-60 high dose rate brachytherapy thermoluminescence dosimetry

Nazeri, A. A. Z. Ahmad and Sani, S. F. Abdul and Ung, N. M. and Almugren, K. S. and Alkallas, F. H. and Bradley, D. A. (2021) Borosilicate glass Co-60 high dose rate brachytherapy thermoluminescence dosimetry. Applied Radiation and Isotopes, 176. ISSN 0969-8043, DOI

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Brachytherapy is commonly used in treatment of cervical, prostate, breast and skin cancers, also for oral cancers, typically via the application of sealed radioactive sources that are inserted within or alongside the area to be treated. A particular aim of the various brachytherapy techniques is to accurately transfer to the targeted tumour the largest possible dose, at the same time minimizing dose to the surrounding normal tissue, including organs at risk. The dose fall-off with distance from the sources is steep, the dose gradient representing a prime factor in determining the dose distribution, also representing a challenge to the conduct of measurements around sources. Amorphous borosilicate glass (B2O3) in the form of microscope cover slips is recognized to offer a practicable system for such thermoluminescence dosimetry (TLD), providing for high-spatial resolution (down to < 1 mm), wide dynamic dose range, good reproducibility and reusability, minimal fading, resistance to water and low cost. Herein, investigation is made of the proposed dosimeter using a 1.25 MeV High Dose Rate (HDR) Co-60 brachytherapy source, characterizing dose response, sensitivity, linearity index and fading. Analysis of the TL glow curves were obtained using the T-max -T-stop method and first-order kinetics using GlowFit software, detailing the frequency factors and activation energy.

Item Type: Article
Funders: Princess Nourah bint Abdulrahman University (RGP-1440-0016) (2)
Uncontrolled Keywords: Brachytherapy; Dosimetry; Microscope glass slide; Thermoluminescence
Subjects: Q Science > QD Chemistry
R Medicine
Divisions: Faculty of Medicine
Faculty of Science
Depositing User: Ms Zaharah Ramly
Date Deposited: 05 Mar 2022 07:16
Last Modified: 05 Mar 2022 07:16

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