Phytochemical constituents from Neolamarckia cadamba (Roxb.) Bosser

Qureshi, Ahmad Kaleem and Liew, Sook Yee and Othman, Noor Aimi and Awang, Khalijah (2021) Phytochemical constituents from Neolamarckia cadamba (Roxb.) Bosser. Biochemical Systematics and Ecology, 96. ISSN 0305-1978, DOI

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Phytochemical study on Neolamarckia cadamba (Roxb.) Bosser has yielded ten indole alkaloids, neolarmarckine A-E (1-5), cadamine (6), 3 beta-isodihydrocadambine (7), angustine (8) and naulafine (9) and harmane (10). The structural elucidation of all the compounds were conducted based on the thorough analysis of spectroscopic data and comparison with reported data. The chemotaxonomic significance of all these compounds were summarized. Among all the indole alkaloids, compound 3-5 were new compounds and isolated from Neolamarckia cadamba (Roxb.) Bosser for the first time. Compounds 1 and 2 were only found in Neolamarckia species while compounds 6 and 7 were only isolated from the family of Rubiaceace. Besides, compound 8 has been found in six genera of Rubiaceae and two genera of Apocynaceae while compound 9 was isolated from Neolamarkia species for the first time. Compound 10 can be found in many genera of Rubiaceae and also more than ten families such as Zygophyllaceae, Cyperaceae, Passifloraceae, Bignoniaceae, Sapotaceae, Elaeagnaceae, Leguminosae, Loganiaceae, Apocynaceae, Combretaceae, Chenopodiaceae, Commelinaceae and Polygalaceae.

Item Type: Article
Funders: undamental Research Grant Scheme (FRGS) (FRGS/1/2018/STG01/UM/02/16)
Uncontrolled Keywords: Neolamarckia cadamba (Roxb.) bosser; Alkaloid; Cadambine; Neolamarckine C-E
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Divisions: Centre for Foundation Studies in Science
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 21 Mar 2022 04:08
Last Modified: 21 Mar 2022 04:08

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