Phang, Zi Hao and Khoo, Saw Sian and Gunasagaran, Jayaletchumi and Ahmad, Tunku Sara Tunku (2021) Clinical outcome of Maggot Debridement Therapy followed by Negative Pressure Wound Therapy for chronic hand wound with Multi-Drug Resistant Organism infection: Two cases and review of the literature. Journal of Orthopaedic Surgery, 29 (3). ISSN 2309-4990, DOI https://doi.org/10.1177/23094990211067302.
Full text not available from this repository.Abstract
The advancement in science and research has led to development of medical maggots which feed exclusively on dead tissue. Medical maggots have three important functions namely debridement, disinfection, and stimulation of wound healing. The modern use of medical maggots now goes by the term ``Maggot Debridement Therapy'' (MDT) for use in wound management. MDT is still used infrequently due to the effectiveness of surgical debridement and antibiotics for treatment of wound infection. Lately, there was emergence of Multi-Drug Resistant Organism (MDRO) likely due to inappropriate antibiotics usage. Maggot secretions have been shown to be effective in inhibiting some MDRO, for example, Methicillin-resistant Staphylococcus aureus, thus making MDT an attractive option for wounds with MDRO. We report two patients with multiple medical comorbidities, diagnosed with serious MDRO Diabetic Hand Infections treated with three cycles of MDT followed by Negative Pressure Wound Therapy.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Maggot; Hand; Infection; Wound; Dressing; Antibiotic resistance |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 24 Feb 2022 01:59 |
| Last Modified: | 24 Feb 2022 01:59 |
| URI: | http://eprints.um.edu.my/id/eprint/26367 |
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