Clinicopathologic presentations of 18 cases of traumatic granulomas

Zain, R.B. and Ti, L.S. (1999) Clinicopathologic presentations of 18 cases of traumatic granulomas. Journal of Dental Research, 78 (5). p. 1172. ISSN 0022-0345,


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A retrospective study of 11 cases of traumatic granulomas was done. The objective of this study is to present the clinicopathological features of traumatic granulomas in some malaysian patients and to compare this data with data from other reported studies, which have been predominantly from Caucasian population. Biopsy records from 1985 to 1998 of 18 cases of traumatic granulomas were obtained. There were 13 male and 5 female patients. The granulomas occured in 38.9 Malay, 38.9 Chinese, 11.1 Indian and 11.1 other ethnic groups. The age of these patients range from 8 to 86 years, with mean of 41.9 ± 17.7 years. The most common location for the lesions was the tongue, other locations were on the floor of mouth-tongue junction, retromolar region, buccal gingiva, lower lip, and anterior mandible with one case presenting with multiple ulcers in different locations. The provisional diagnoses given by the clinicians prior to biopsy include traumatic ulcer, squamous cell carcinoma, lichen planus, recurrent apthous ulcer, Wegener's granulomatosis, pyogenic granuloma, infectious ulcer (tuberculosis) and squamous cell papilloma. Some of the patients (66.7) have past/current medical condition, which include diseases of the endocrine, gastrointestinal, cardiovascular system, malignancy, venereal disease, autoimmune disease, and one Human Immunodeficiency Virus positive patient. Histologically, pseudoinvasion of plasma cells and histiocytes between muscle bundles are evident in all cases. Eosinophils are consistently found in all but one case. In conclusion, most of the clinical and histological features present in these cases are comparable to cases in Caucasian reported in the literature.

Item Type: Article
Additional Information: Times Cited: 1 Zain, RB Ti, LS
Uncontrolled Keywords: Oral Squamous Cell Carcinoma, Oscc, Lichenoid Lesions, Lichen Planus, Oral Cancer, Oral Tumours, Pemphigus, Traumatic Eosinophilic Granuloma, Aphthous Ulcers, Oral Mucosal Lesions, Betel Chewers Mucosa, Betel Quid Related Lesions, Betel Quid, Areca Quid, Tobacco Quid, Oral Cancer Screening, Training And Calibration, Early Detection, Oral Cancer Awareness, Biobanking, Tissue Bank, Databank, Oral Cancer, Tissue Bank, Research Credibility, Research Ethics
Subjects: R Medicine > RK Dentistry > Oral surger
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Prof. Dr. Rosnah Mohd Zain
Date Deposited: 08 Feb 2012 03:22
Last Modified: 20 Oct 2014 08:21

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