Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases

Zain, R.B. and Fei, Y.J. (1990) Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases. Oral Surgery Oral Medicine and Oral Pathology, 70 (4). pp. 466-470. ISSN 1079-2104, DOI .


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Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5 of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5) or the mixed (cellular and collagenous) type (44.6). It was also found that 36 of the lesions were ulcerated, and, of these, 79.5 were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.

Item Type: Article
Additional Information: Department of Oral Pathology and Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya
Uncontrolled Keywords: Oral squamous cell carcinoma, OSCC, lichenoid lesions, lichen planus, oral cancer, oral tumours, pemphigus, traumatic eosinophilic granuloma, aphthous ulcers, oral mucosal lesions, betel chewers mucosa, betel quid related lesions, betel quid, areca quid, tobacco quid, oral cancer screening, training and calibration, early detection, oral cancer awareness, biobanking, tissue bank, databank, oral cancer, tissue bank, research credibility, research ethics, article; classification; fibrosis; gingiva; histology; histopathology, human, major clinical study, methodology, mouth mucosa, priority journal
Subjects: R Medicine > RK Dentistry > Oral surger
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Prof. Dr. Rosnah Mohd Zain
Date Deposited: 02 Feb 2012 09:02
Last Modified: 21 Oct 2014 01:49

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