Evaluation of Ge-doped silica fibre TLDs forin vivodosimetry during intraoperative radiotherapy

Moradi, Farhad and Ung, Ngie Min and Mahdiraji, Ghafour Amouzad and Khandaker, Mayeen Uddin and See, Mee Hoong and Taib, Nur Aishah Mohd and Bradley, David Andrew (2019) Evaluation of Ge-doped silica fibre TLDs forin vivodosimetry during intraoperative radiotherapy. Physics in Medicine & Biology, 64 (8). 08NT04. ISSN 0031-9155, DOI https://doi.org/10.1088/1361-6560/ab0d4e.

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Official URL: https://doi.org/10.1088/1361-6560/ab0d4e


Ge-doped silica fibre (GDSF) thermoluminescence dosimeters (TLD) are non-hygroscopic spatially high-resolution radiation sensors with demonstrated potential for radiotherapy dosimetry applications. The INTRABEAM® system with spherical applicators, one of a number of recent electronic brachytherapy sources designed for intraoperative radiotherapy (IORT), presents a representative challenging dosimetry situation, with a low keV photon beam and a desired rapid dose-rate fall-off close-up to the applicator surface. In this study, using the INTRABEAM® system, investigations were made into the potential application of GDSF TLDs for in vivo IORT dosimetry. The GDSFs were calibrated over the respective dose- and depth-range 1 to 20 Gy and 3 to 45 mm from the x-ray probe. The effect of different sizes of spherical applicator on TL response of the fibres was also investigated. The results show the GDSF TLDs to be applicable for IORT dose assessment, with the important incorporated correction for beam quality effects using different spherical applicator sizes. The total uncertainty in use of this type of GDSF for dosimetry has been found to range between 9.5% to 12.4%. Subsequent in vivo measurement of skin dose for three breast patients undergoing IORT were performed, the measured doses being below the tolerance level for acute radiation toxicity. © 2019 Institute of Physics and Engineering in Medicine.

Item Type: Article
Uncontrolled Keywords: Ge-doped silica fibre; intraoperative radiotherapy; Monte Carlo simulation; skin dose; thermoluminescent dosimeter
Subjects: Q Science > QC Physics
R Medicine
Divisions: Faculty of Medicine
Faculty of Science > Department of Physics
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Mar 2020 04:18
Last Modified: 04 Mar 2020 04:18
URI: http://eprints.um.edu.my/id/eprint/23964

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