Synthesis and Characterization of Magnetic Nanostructured Lipid Carriers (mNLCs) for Drug Delivery

Akhtar, Naseem and Teo, Yin Yin and Najeeb, Mansoor Ani and Ahmad, Zubair and Shah, Zarbad and Hasan, Md Anwarul (2018) Synthesis and Characterization of Magnetic Nanostructured Lipid Carriers (mNLCs) for Drug Delivery. International Journal of Electrochemical Science, 13 (12). pp. 12040-12048. ISSN 1452-3981, DOI

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Magnetic nanoparticles (MNPs) are a class of nanoparticles, which can be manipulated using magnetic fields. Currently, MNPs are recognized as one of the most important mode as a drug carrier while they can also be potentially used as carriers for gene delivery. In this article, magnetic nanostructured lipid carriers (mNLCs) are prepared through co-precipitation method. The particle size and zeta potential, structure and thermal properties of the MNPS have been studied. The produced MNPs were also hydrophobically modified with a long chain of fatty acid namely lauric acid. These modified MNPs were mixed with nanostructured lipid carriers (NLCs) to form mNLCs. The heat capacity and flow of mNLCs was profligate in the presence of a magnetic field which is a worthy attribute for targeted drug delivery applications.

Item Type: Article
Funders: GCC-2017-005 grant by Qatar University, NPRP9-144-3-021 grant funded by the Qatar National Research Fund (a part of Qatar Foundation)
Uncontrolled Keywords: Drug delivery; Magnetic nanoparticles (MNPs); Magnetic nanostructured lipid carriers (mNLCs)
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
T Technology > TJ Mechanical engineering and machinery
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 27 Sep 2019 02:47
Last Modified: 27 Sep 2019 02:47

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