Electronic profiling of algae-derived DNA using DNA-specific Schottky diode

Azmi, Siti Zulfikriyah and Vello, Vejeysri and Rizan, Nastaran and Krishnasamy, Jegenathan and Talebi, Sara and Gunaselvam, Priya and Iqbal, Suhaina Nashath Mohamed and Yew, Chan Yen and Phang, Siew Moi and Iwamoto, Mitsumasa and Periasamy, Vengadesh (2018) Electronic profiling of algae-derived DNA using DNA-specific Schottky diode. Applied Physics A, 124 (8). p. 559. ISSN 0947-8396, DOI https://doi.org/10.1007/s00339-018-1972-z.

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Official URL: https://doi.org/10.1007/s00339-018-1972-z


In recent years, application of deoxyribonucleic acid (DNA) in electronics has created much interest among researchers because of its unique properties. Important applications involve DNA-based sensors and devices. There are several ways to detect and identify various species of organisms such as polymerase chain reaction, sequencing, as well as microarray techniques. However, these techniques are susceptible to sample contamination, misleading results besides being expensive, and difficult to handle. Herein, we present a novel and low-cost identification method for algae-derived DNA using the electronic properties of DNA. For the first time, current–voltage (I–V) characteristics for selected algae species using DNA-specific diodes were obtained and its corresponding diode parameters (turn-on or threshold voltage, shunt and series resistance, knee voltage, breakdown voltage, as well as breakdown current) were then calculated. We believe this novel technique will benefit mankind in future in terms of medical technology involving pathology and healthcare.

Item Type: Article
Funders: University of Malaya Centre of Excellence (UMCoE) Research University Grant (RU003-2017), Fundamental Research Grant Scheme, FRGS (FP038-2017A), University of Malaya Postgraduate Research Fund, PPP (PG125-2015A)
Uncontrolled Keywords: Breakdown currents; Diode parameters; Identification method; Knee voltage; Medical technologies; Novel techniques; Schottky diodes; Shunt and series resistance
Subjects: Q Science > Q Science (General)
Q Science > QC Physics
Q Science > QD Chemistry
Q Science > QH Natural history
Divisions: Faculty of Science > Department of Chemistry
Faculty of Science > Department of Physics
Faculty of Science > Institute of Biological Sciences
Deputy Vice Chancellor (Research & Innovation) Office > Institute of Ocean and Earth Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 18 Sep 2019 01:25
Last Modified: 18 Sep 2019 01:25
URI: http://eprints.um.edu.my/id/eprint/22394

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