Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications

Ramesh, Singh and Loo, Zi Zhen and Tan, Chou Yong and Chew, Wai Jin Kelvin and Ching, Yern Chee and Tarlochan, Faris and Chandran, Hari and Krishnasamy, Sivakumar and Bang, Le Thi and Sarhan, Ahmed Aly Diaa Mohammed (2018) Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications. Ceramics International, 44 (9). pp. 10525-10530. ISSN 0272-8842, DOI

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In this work, the viability of producing biogenic hydroxyapatite from bio-waste animal bones, namely bovine (cow), caprine (goat) and galline (chicken), through a heat treatment process has been investigated. The animal bones were locally sourced, cleaned to remove collagen and subsequently heat treated in air atmosphere at different temperatures ranging from 600 °C to 1000 °C. From the range of sintering temperatures investigated, it was found that hydroxyapatite derived from bovine bone showed good thermal stability while those produced from caprine and galline bones exhibited phase instability with traces of tri-calcium phosphate (TCP) being detected after heat treatment beyond 700 °C. The porous nature of the bone samples can be observed from the microstructures obtained and supported by low relative density. Heating the bovine and caprine bones at selected temperatures yielded porous HA body, having hardness values that are comparable with human cortical bone. However, the sintered galline bone sample showed higher porosity levels and low hardness when compared to the other two bone types.

Item Type: Article
Uncontrolled Keywords: Hydroxyapatite; Animal bones; Heat treatment; Microstructure; Phase analysis; Vickers hardness
Subjects: R Medicine
T Technology > TJ Mechanical engineering and machinery
Divisions: Faculty of Engineering
Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 16 Apr 2019 07:50
Last Modified: 16 Apr 2019 07:50

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