Renewable resources-based approach to biantennary glycolipids

Tabandeh, Mojtaba and Salman, Abbas Abdulameer and Goh, Ean Wai and Heidelberg, Thorsten and Hussen, Rusnah Syahila Duali (2018) Renewable resources-based approach to biantennary glycolipids. Chemistry and Physics of Lipids, 212. pp. 111-119. ISSN 0009-3084, DOI

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A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated formation of vesicles with high assembly stability. A relatively narrow bimodal size distribution of the latter, which turns into a narrow unimodal distribution of small vesicles upon addition of an ionic cosurfactant, suggests potential for a vesicular drug delivery system.

Item Type: Article
Funders: University of Malaya under grants RP024-2012B, RG264-13AFR, and PG149‐2015A, Malaysian Ministry of Education under research grant FP032-2013B
Uncontrolled Keywords: Oleic acid functionalization; Biantennary glycolipids; Guerbet glycosides; Biosurfactant assembly; Vesicles
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Mar 2019 07:44
Last Modified: 04 Mar 2019 07:44

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