Functionalized glycolipids for potential bioconjugation of vesicles

Tabandeh, Mojtaba and Goh, Ean Wai and Salman, Abbas Abdulameer and Heidelberg, Thorsten and Hussen, Rusnah Syahila Duali (2018) Functionalized glycolipids for potential bioconjugation of vesicles. Carbohydrate Research, 469. pp. 14-22. ISSN 0008-6215, DOI

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Two azide-terminated oligoethylene oxide spacered glycolipids have been synthesized, and their assembly behavior has been studied in comparison to the corresponding base surfactants. The results suggest potential of the Guerbet lactoside-based compound for targeted drug delivery, while a coiling of the ethylene oxide linker disfavors the application of the glucoside.

Item Type: Article
Funders: University of Malaya under grants RP024-2012B, RG264-13AFR, RG383-17AFR and PG093-2013A, Malaysian Ministry of Higher Education under research grant FP032-2013B
Uncontrolled Keywords: Biantennary glycolipid; Targeted drug delivery; Vesicle bioconjugation; CLICK chemistry coupling; Ethylene oxide spacer; Surfactant assembly
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Mar 2019 07:39
Last Modified: 04 Mar 2019 07:42

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