Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study

Uchenna, Uzukwu Emmanuel and Shori, Amal Bakr and Baba, Ahmad Salihin (2018) Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study. Journal of Ayurveda and Integrative Medicine, 9 (4). pp. 258-265. ISSN 0975-9476, DOI https://doi.org/10.1016/j.jaim.2017.06.004.

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Official URL: https://doi.org/10.1016/j.jaim.2017.06.004


Background: The tamarind seeds have a lot of nutrients that may be used to control cholesterol or glucose levels. Objective(s): The effects of tamarind seeds (T) on lipid and carbohydrate metabolism in rats were studied. Rats were offered basal diet (BD) with T (2%, 4% or 8%) or without T. Materials and methods: Feeding and growth performance in rats were measured and samples of liver and blood were analyzed for glycogen content and levels of cholesterol and glucose respectively. Results: The inclusion of T in the diet influences the feeding and growth performance in rats. The serum cholesterol level was reduced (p < 0.05) in Sprague Dawley (SD) rats fed on basal diet (BD) containing 4% and 8% T (0.24 ± 0.14 g/l and 0.31 ± 0.06 g/l respectively) compared to control (0.79 ± 0.04 g/l). The serum glucose levels in the spontaneous hypertensive rats (SHR) was lower (50.74 ± 2.50 mg/dl; p < 0.05) than control (93.52 ± 10.83 mg/dl) at 4% T. Incorporation of increasing doses of T resulted in linear increase of glycogen storage in livers of SD rats fed on BD and high sucrose diet. Conclusion: Tamarind seeds can lower blood glucose and serum cholesterol and enhance storage of glycogen in rats.

Item Type: Article
Funders: IPPP University of Malaya
Uncontrolled Keywords: Tamarind seeds; Glucose; Glycogen; Cholesterol; Spontaneous hypertensive rats; Feeding and growth performance
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Feb 2019 02:18
Last Modified: 22 Feb 2019 02:18
URI: http://eprints.um.edu.my/id/eprint/20444

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