Metabolomic profiles of tropical Chlorella species in response to physiological changes during nitrogen deprivation

Vello, Vejeysri and Chu, Wan Loy and Lim, Phaik Eem and Majid, Nazia Abdul and Phang, Siew Moi (2018) Metabolomic profiles of tropical Chlorella species in response to physiological changes during nitrogen deprivation. Journal of Applied Phycology, 30 (6). pp. 3131-3151. ISSN 0921-8971, DOI

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Chlorella species are known to be potential algal candidates for biodiesel production due to their ability to store lipids and their natural metabolic versatility. This study assessed the photosynthetic performance, biochemical composition, and metabolomic profiles of tropical Chlorella UMACC050 harvested from different growth phases in batch culture, grown under nitrogen-replete, and nitrogen-depleted conditions. Physiological data suggested that growth and photosynthetic efficiency were affected during nitrogen deprivation. Nitrogen deprivation resulted in a decrease in biomass productivity and an increase of lipid content. Nitrogen-depletion resulted in an increase in saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA), especially C16:0, C18:0, and C18:1, at the expense of polyunsaturated fatty acids (PUFA). Changes in the metabolomic profiles suggested that there was nitrogen assimilation from proteins and photosynthetic machinery, together with repartitioning of carbon into carbohydrates and lipids in response to nitrogen depletion. Overall, our results expand the current understanding of metabolomics of Chlorella species and provide valuable insights into their lipid accumulation during nitrogen deprivation, which is important for optimization of lipid productivity in the tropical environment.

Item Type: Article
Funders: Postgraduate Research Fund (Ref: PS301/2010B and PV032/2011B), Malaysian Palm Oil Board (MPOB, Ref: 55-02-03-1054), AMIC (Algae Bioenergy, Ref: PV001-2013)
Uncontrolled Keywords: Algae; Biodiesel; Chlorella; Chlorophyta; Fatty acid; Metabolomics; Nitrogen
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 21 Feb 2019 04:10
Last Modified: 21 Feb 2019 04:10

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